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Improved Prognosis for Patients with Ewing Sarcoma in the Sacrum Compared with the Innominate Bones by Asle Charles Hesla, Panagiotis Tsagozis, Nina Jebsen,

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Presentation on theme: "Improved Prognosis for Patients with Ewing Sarcoma in the Sacrum Compared with the Innominate Bones by Asle Charles Hesla, Panagiotis Tsagozis, Nina Jebsen,"— Presentation transcript:

1 Improved Prognosis for Patients with Ewing Sarcoma in the Sacrum Compared with the Innominate Bones by Asle Charles Hesla, Panagiotis Tsagozis, Nina Jebsen, Olga Zaikova, Henrik Bauer, and Otte Brosjö J Bone Joint Surg Am Volume 98(3):199-210 February 3, 2016 ©2016 by The Journal of Bone and Joint Surgery, Inc.

2 Flowchart showing differences in local treatment for patients with Ewing sarcoma of the sacrum and patients with Ewing sarcoma of the innominate bones. Asle Charles Hesla et al. J Bone Joint Surg Am 2016;98:199-210 ©2016 by The Journal of Bone and Joint Surgery, Inc.

3 Local recurrence-free survival analysis of 110 pelvic Ewing sarcomas showing cumulative five- year local recurrence-free survival rates of 95% and 85%, respectively, for sacral and innominate bone tumors (log-rank test, p = 0.18). Asle Charles Hesla et al. J Bone Joint Surg Am 2016;98:199-210 ©2016 by The Journal of Bone and Joint Surgery, Inc.

4 Disease-free survival analysis of 117 pelvic Ewing sarcomas showing cumulative five-year disease-free survival rates of 66% and 40%, respectively, for sacral and innominate bone tumors (log-rank test, p = 0.01). Asle Charles Hesla et al. J Bone Joint Surg Am 2016;98:199-210 ©2016 by The Journal of Bone and Joint Surgery, Inc.

5 Overall survival analysis of 117 pelvic Ewing sarcomas showing cumulative five-year overall survival rates of 65% and 49%, respectively, for sacral and innominate bone tumors (log-rank test, p = 0.08). Asle Charles Hesla et al. J Bone Joint Surg Am 2016;98:199-210 ©2016 by The Journal of Bone and Joint Surgery, Inc.

6 The cumulative overall survival of patients with intralesional or marginal margin without radiation treatment compared with patients with intralesional or marginal margin with postoperative radiation treatment (log-rank test, p = 0.04). Asle Charles Hesla et al. J Bone Joint Surg Am 2016;98:199-210 ©2016 by The Journal of Bone and Joint Surgery, Inc.

7 The cumulative overall survival of patients with wide margin without radiation treatment compared with patients with intralesional or marginal margin with postoperative radiation treatment (log-rank test, p = 0.91). Asle Charles Hesla et al. J Bone Joint Surg Am 2016;98:199-210 ©2016 by The Journal of Bone and Joint Surgery, Inc.


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