2. Today we take many things in science for granted. Many experiments have been performed and much knowledge has accumulated that people weren’t always aware of. For centuries, people based their beliefs on their interpretations of what they saw going on in the world around them without testing their ideas to determine the validity of these theories — in other words, they didn’t use the scientific method to arrive at answers to their questions. Rather, their conclusions were based on untested observations. In the public eye, controversy is considered an act that illustrates that a response is needed or that the "new" claims are inadequate because they cannot "prove" anything.

3.  Observation: Every year in the spring, the Nile River flooded areas of Egypt along the river, leaving behind nutrient-rich mud that enabled the people to grow that year’s crop of food. However, along with the muddy soil, large numbers of frogs appeared that weren’t around in drier times.  Conclusion?

4.  It was perfectly obvious to people back then that muddy soil gave rise to the frogs.

5.  Observation: In many parts of Europe, medieval farmers stored grain in barns with thatched roofs (like Shakespeare’s house). As a roof aged, it was not uncommon for it to start leaking. This could lead to spoiled or moldy grain and, of course there were lots of mice around.  Conclusion?

6.  It was obvious to them that the mice came from the moldy grain.

7.  Observation: In the cities, there were no sewers, no garbage trucks, no electricity, and no refrigeration. Sewage flowed in the gutters along the streets, and the sidewalks were raised above the streets to give people a place to walk. In the intersections, raised stepping stones were strategically placed to allow pedestrians to cross the intersection, yet were spaced such that carriage wheels could pass between them. In the morning, the contents of the chamber pots were tossed out the nearest window. Food was purchased and prepared on a daily basis, and when people were done eating a meal, the bones and left- overs were tossed out the window, too. A chivalrous gentleman always walked closest to the street when escorting a woman, so if a horse and carriage came by and splashed up the filth flowing in the gutters, it would land on him, and not the lady’s expensive silk gown (many of these gowns were so ornately embroidered that they were not easily washable, and neither washing machines nor dry cleaners existed).

8.  Many cities also had major rat problems. People back then may or may not have not connected the presence of rats with the spread of Bubonic Plague (Black Death, a dreaded and fatal disease), but they were probably bothered by the rats chewing on things and by the rat fleas biting them (just as cat/dog owners, even now, are bitten by the offspring of their pet’s fleas). People may not have realized that the Plague was spread by the bites of those fleas, but I imagine they knew that if only they could get rid of the rats, the pesky fleas would soon disappear, too — hence the story of the Pied Piper of Hamelin, Germany, leading all the rats out of town.  Conclusion?

9.  Conclusion: Obviously, all the sewage and garbage turned into the rats.

10.  Observation: Since there were no refrigerators, the mandatory, daily trip to the butcher shop, especially in summer, meant battling the flies around the carcasses. Typically, carcasses were “hung by their heels,” and customers selected which chunk the butcher would carve off for them.  Conclusion?

11.  Conclusion: Obviously, the rotting meat that had been hanging in the sun all day was the source of the flies.

12.  Recipe for bees: Kill a young bull and bury it in an up right position so that its horns protrude from the ground. After a month, a swarm of bees will fly out of the corpse.  Why might this recipe have been published?

13.  Jan Baptista van Helmont’s recipe for mice: Place a dirty shirt or some rags in an open pot or barrel containing a few grains of wheat or some wheat bran, and in 21 days, mice will appear. There will be adult males and females present, and they will be capable of mating and reproducing more mice.  Why might this recipe have been published?

14. The idea that organisms originate directly from nonliving matter. "life from nonlife" https://www.youtube.com/watch?v=WNB yRghR6sw

16. Francesco Redi - One of the first to disprove spontaneous generation An Italian doctor who proved maggots came from flies. (Italian 1668)

18. Set-up 3 jars with rotting meat 1. Open top 2. Sealed with lid 3. Covered with cloth Observations 1. Maggots 2. No maggots 3. No maggots

20. Set-up Nutrient broth heated 1.Flask left open 2.Flask sealed Observations 1.Bacteria grew 2.No bacteria grew

22. Set-up Nutrient broth heated 1.Flask with curved neck 2.Flask with straight neck Observations 1.No dust could reach broth, no bacteria grew 2.Dust settled, bacteria grew

23. The experiments of Redi, Spallanzani, and Pasteur showed the life does not arise spontaneously LIFE must come from LIFE These experiments supported the theory of biogenesis

24. BIO= life GENESIS= the beginning

25. The idea that life arises from pre- existing cells