1. 1

2. CANCER Cancer is not just one disease What is cancer?
More than 200 different types of cancer have been identified
CANCER

3. Defining cancer
Cancer is an accumulation of abnormal cells that multiply through uncontrolled cell division and spread to other parts of the body by invasion and/or distant metastasis via the blood and lymphatic system
Normal cells
Abnormal cells
Tumour growth
Metastasis
Uncontrolled cell division
Invasion into surrounding tissues
Spread via blood or lymphatic system

4. Incidence of cancer across the globe (2008, estimate)1
Evidence: Ferlay2008_CancerIncidenceContinent_GLOBOCAN, Ferlay2008_CancerIncidence2008_2030_GLOBOCAN
1. Ferlay J, Shin HR, Bray F, Forman D, Mathers C and Parkin DM. GLOBOCAN 2008 v2.0, Cancer Incidence and Mortality Worldwide: IARC Cancer Base No.10 [Internet]. Lyon, France: International Agency for Research on Cancer; Available from: accessed on 06/06/2013.

5. Changing prevalence of cancer
Global cancer incidence and mortality rates continue to rise1
25 M people living with cancer*2
75 M predicted to be living with cancer2
2030
21.3 M
2008
13.1 M
GROWING AND AGEING POPULATION
12.7 M
ADOPTION OF UNHEALTHY LIFESTYLES
7.6 M
Evidence: Ferlay2008_CancerIncidence2008_2030_GLOBOCAN; Ferlay2008_CancerMortality2008_2030_GLOBOCAN; IARC 2008 (foreword; NB Cannot highlight relevant text).
IMPROVEMENT IN DIAGNOSIS/SCREENING
CASES
DEATHS
2002
*Diagnosed in last 5 years
2030
Ferlay J, Shin HR, Bray F, Forman D, Mathers C and Parkin DM. GLOBOCAN 2008 v2.0, Cancer Incidence and Mortality Worldwide: IARC Cancer Base No.10 [Internet]. Lyon, France: International Agency for Research on Cancer; Available from: accessed on 14/01/2013.
The International Agency for Research on Cancer. World Cancer Report Available from: accessed on 06/06/2013.

6. Common cancers in men and women worldwide1
Evidence: CancerIncidenceInMenAndWomenByCancerType_GLOBOCAN
1. Ferlay J, Shin HR, Bray F, Forman D, Mathers C and Parkin DM. GLOBOCAN 2008 v2.0, Cancer Incidence and Mortality Worldwide: IARC Cancer Base No.10 [Internet]. Lyon, France: International Agency for Research on Cancer; Available from: accessed on 06/06/2013.

7. Global cancer mortality
Approximately 7.56 million people died from cancer in 2008,1 accounting for 13% of all deaths (from any cause)2
Lung, stomach, liver, colorectal and female breast cancers
cause 50% of all
cancer deaths1
Evidence: Ferlay2008_CancerMortalityInMenAndWomenByType_GLOBOCAN;
AmericanCancerSociety_GlobalCancerFacts, table 1 (NB Cannot highlight)
Ferlay J, Shin HR, Bray F, Forman D, Mathers C and Parkin DM. GLOBOCAN 2008 v2.0, Cancer Incidence and Mortality Worldwide: IARC Cancer Base No.10 [Internet]. Lyon, France: International Agency for Research on Cancer; Available from: accessed on 06/06/2013.
American Cancer Society. Global Cancer Facts and Figures 2nd Edition. Atlanta: American Cancer Society; 2011.