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XYZ 3×  mode locked Nd:YAG air SF 6 gas water Matrix-Less MALDI Laser-Microstructuring of Si Vertes – GWUMC – 01/24/07.

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Presentation on theme: "XYZ 3×  mode locked Nd:YAG air SF 6 gas water Matrix-Less MALDI Laser-Microstructuring of Si Vertes – GWUMC – 01/24/07."— Presentation transcript:

1 XYZ 3×  mode locked Nd:YAG air SF 6 gas water Matrix-Less MALDI Laser-Microstructuring of Si Vertes – GWUMC – 01/24/07

2 Nanoreactor for Ion Chemistry h Low fluence => protonation Medium fluence => alkalination Vertes – GWUMC – 01/24/07

3 In-Source Decay High fluence => ISD bradykinin P 14 R Chen and Vertes Anal. Chem., 2006, 78, 5835. Fluence Vertes – GWUMC – 01/24/07

4 composite images spectra IR Laser beam to MS Atmospheric Pressure MALDI Imaging Pulsed dynamic focusing Metabolomics Proteomics Vertes – GWUMC – 01/24/07

5 SucroseGlucose/Fructose Toluidine Blue O Optical Sucrose Glucose/Fructose Toluidine Blue O Metabolic Imaging Plant transpiration experiment Vertes – GWUMC – 01/24/07

6 CID - m/z 145.01 Lily petal MS/MS for Metabolites Collision induced dissociation x-y scanning z positioning NIST Database  -ketoglutaric acid 30 metabolites identified Vertes – GWUMC – 01/24/07

7 Stability of Electrosprays Varicose breakup Lateral kink breakup Side jet Vertes – GWUMC – 01/24/07

8 Order-Chaos-Order 170  s Axial III to Axial II Transition Vertes – GWUMC – 01/24/07

9 Marginean, et al., Phys. Rev. Lett., 2006, 97, 064502. Return Maps Vertes – GWUMC – 01/24/07


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