1. GI System & Respiratory System
EXAM REVIEW
GI System & Respiratory System

2. HCl Production Key Info to Note:
Parietal cells contain Carbonic Anhydrase (CAH)
H+ pumped into stomach lumen by H-K ATPase
HCO3- exchanged for Cl- (chloride shift)
Alkaline tide in blood due to increase HCO3- (Increase pH)

3. Cl- Cl- K+ HCl HCO3- H+ CO2 CO2+H2OH2CO3 BLOOD PARIETAL CELL
LUMEN OF STOMACH
Cl-
Cl- K+
HCl
HCO3- H+
CO2
CO2+H2OH2CO3

4. Protein Digestion

5. Parietal Cell stimulated
Pyloric Gland
Gastric Gland
Pepsinogen
Food enters Stomach
Secrete Gastrin
Chief Cell stimulated
G Cell Stimulated
Gastric pH
HCl
Parietal Cell stimulated
Partially digested protein
Pepsin (Pepsinogen+HCl)
= Parietal Cell
= G Cell
= Chief Cell

6. Fat Digestion

7. Gastric Motility
Suppress GM? 1. 2. 3.
Activate GM?

8. Pancreatic Enzymes Trypsinogen Chymotrypsinogen Precarboxypeptidase
Enterokinase
Trypsin
Trypsin
Chymotrypsin
Trypsin
Carboxypeptidase
Others:
Pancreatic Lipase
Pancreatic Amylase

9. O2 Transport On your own time, define the following gas laws: HENRY’S
BOYLE’S
DALTON’S
**Be able to relate these to respiration

10. Hemoglobin-O2 Curve Affinity Reduced: by LOW pH by HIGH temperature
by HIGH CO2 concentration