1. CIP HPC http://hpc.cip.cgiar.org

2. CIP - HPC HPC = High Performance Computer It’s not a regular computer, it’s bigger, faster, more powerful, and more expensive. We would like it to be a Super computer but it is rather small so, High Performance Computer http://hpc.cip.cgiar.org

3. A Computer Cluster You regular PCA computer cluster Front-end node Compute-0-0Compute-0-1Compute-0-2 1 CPU 1 or 2 Hard disks Some memory 512MB,.. 1GB,.. http://hpc.cip.cgiar.org

4. CIP’s HPC: A High Performance Computer CIP’s HPC is a computer cluster: A group of connected computers that work together as a unit. Some computer clusters are called “Super Computers” specially when they have 50, 100, thousands of nodes, or more http://hpc.cip.cgiar.org

5. CIP’s HPC: A High Performance Computer From: http://www.top500.org/ we can notice that many of the TOP 500 Supercomputers are Linux Clusters. “MareNostrum” from the Barcelona Supercomputer Center (The forth fastest computer in the world (Nov. 2004) with 3564 CPUs) 8 th by May 2006

6. 4 Nodes (1u cases) 2 AMD Opteron 64 bits1.8 Ghz Cpu’s in each Node 4 GB Ram on each Node 750 GB Hard Disk in the front- end 80 GB Hard disk on each compute-node CIP’s HPC: Hardware review… http://hpc.cip.cgiar.org

8. CIP HPC The Software http://hpc.cip.cgiar.org

9. Linux Operating System (Rocks Clusters), intended for command line use. MPI and LSF for parallel processing Java Tomcat / PHP / Mysql / Perl Paracel Blast Structure, R, any software capable of running in Linux CIP’s HPC: Software Review http://hpc.cip.cgiar.org

10. CIP HPC Speed

11. Structure Performance http://hpc.cip.cgiar.org

13. Using CIP HPC

15. Providing Easy Access to users Front-end node Compute-0-0 Compute-0-2 Private Network Interface http://hpc.cip.cgiar.org Compute-0-1 Command line Happy User Client Program Web Pages

16. CIP HPC Web http://hpc.cip.cgiar.org

17. BLAST at CIP HPC http://hpc.cip.cgiar.org

18. BLAST: Basic Local Alignment Search Tool finds regions of local similarity between sequences Compares nucleotide or protein sequences to sequence databases and calculates the statistical significance of matches Can be used to infer functional and evolutionary relationships between sequences as well as help identify members of gene families. http://hpc.cip.cgiar.org

19. Advantages of performing Blast at CIP HPC Dedicated server, faster results Searches against specific databases (potato, tobacco, sweet potato), more accurate results. We can add sequence databases to the HPC as requested by users. http://hpc.cip.cgiar.org

20. http://hpc.cip.cgiar.org/bwb

30. The End