1. Interactive analysis of lists …on the web Raymond Ripp 19 février 2013

2. Data and Tools  GxDb  ImAnno  Gscope  GO  SM2PH  EvoluCode  …  /biolo/…  PHP programs PipeWork DoOnlist HtmlTable RadarGenerator StringInteractome GoGet CytoscapeWeb DecoreTree

3. Example 1 : a PipeWork to Combine Lists of Genes  How to combine lists of genes from ImAnno sieves (search tool using SQL queries) Transcriptomic Expression (GxDb Web Service) Diseases related genes (from previously stored lists)  With Union, Intersection, AnotB, …

4. sieves Cochlea Sacculus Utriculus url Select Store cochlea sacculus utriculus other Select Disease Jax Ihr Sanger All ISH Annotation Intersection GenePaintGenes Information Intersection Transcriptomic Diseases … more details

5. Output cadre sieves Cochlea Sacculus Utriculus url action Union Inter AnotB BnotA organ key action Union Inter AnotB BnotA Select Store EGEcoch EGEsac EGEutri EGEother action Union Inter AnotB BnotA Select Disease Jax Ihr Sanger All What to display name,descript,entrez,ege,go FromSieves UnionInter AnotBnotA GenePaintgenes UnionInter AnotBnotA HtmlTable FromStore

7. Output cadre sieves Cochlea Sacculus Utriculus url action Union Inter AnotB BnotA organ key action Union Inter AnotB BnotA Select Store EGEcoch EGEsac EGEutri EGEother action Union Inter AnotB BnotA Select Disease Jax Ihr Sanger All What to display name,descript,entrez,ege,go FromSieves UnionInter AnotBnotA GenePaintgenes UnionInter AnotBnotA HtmlTable FromStore

8. Output cadre sieves Cochlea Sacculus Utriculus url action Union Inter AnotB BnotA organ key action Union Inter AnotB BnotA Select Store EGEcoch EGEsac EGEutri EGEother action Union Inter AnotB BnotA Select Disease Jax Ihr Sanger All What to display name,descript,entrez,ege,go FromSieves UnionInter AnotBnotA GenePaintgenes UnionInter AnotBnotA HtmlTable FromStore

9. ImAnno Gene List

10. HtmlTable as output of the PipeWork

11. PipeWork … merci à  Laetitia Poidevin  Nicolas Gagnière  Guillaume Berthommier

12. Example2 : PipeWork ClusterComposition

13. HtmlTable

14. From an HtmlTable to DoOnList

15. DoOnList

16. DoOnList Help

17. From DoOnList to RadarGenerator

18. RadarGenerator

19. From DoOnList to GO

21. From DoOnList to StringInteractome

22. organism=Mus_musculus … don’t forget to specify the organism

23. StringInteractome Summary

26. From DoOnList to EvoluCode

29. DoOnList Help

30. From ImAnno to Itol From Itol to DecoreTree

34. http://lbgi.fr/fed

35. Paste your gene list to StringInteractome

37. Conclusion … and To Do  It works …  The user can start with his own lists  The analysis tools create new lists  It allows to combine different web sites and systems  The user can store, restore and download his data  Test it on real cases We have to :  Organize user’s data  Allow multi sessions  Add new functionalities  Use it intensively. merci.