1. Unit 1- Microbiology A. Timeline 1. Look for important occurrences
a. plagues
b. advent of the microscope
c. Pasteurella pestis- Bubonic plague
d. Vaccinations- Jenner & Smallpox

2. d. Remember Redi and his maggots?
2. Biogenesis vs. Abiogenesis a. Living things can come from nonliving things b. Aristotle (600 BC) & van Helmont (1600’s) c. NO ONE discounted Aristotle!
d. Remember Redi and his maggots?
e. Needham- response to Redi using the microscope
f. Spallanzanni- fixed Needham’s mistake
=BUT, eliminated “living factor”
g. Who solved the problem?
-Louis Pasteur!

3. 5. Pasteur studies fermentation: C6H12O6=>C2H5OH + CO2
3. Bacteria are shown to move through the air 4. Principles applied to health and infections a. Surgery & childbirth b. Concept of sterilization- 165 F. for 15 min.
5. Pasteur studies fermentation:
C6H12O6=>C2H5OH + CO2
(ethyl alcohol)
6. Microbes get classified:
-Bacillus (rod)
-Coccus (round)
-Spirillum (spiral)

4. Bacterial examples:
E. coli

5. 7. New discoveries become smaller and chemically specific 8
7. New discoveries become smaller and chemically specific 8. Bacteria were found to be giving off toxins a. poison b. followed by antitoxins in 1840
9. Chemical means of “coloring bacteria-
a. Gram stain
b. We’ll do this!
10. Discovery of VIRUSES at the turn of the century
-(even though we could not see them)

6. 11. Discovery of the body’s immune system a. antibodies b
11. Discovery of the body’s immune system a. antibodies b. histamines- led to the discovery of….?
12. Discovery of antibiotics
a. By….?
b. method of discovery-
13. Viruses finally seen in the 1940s after the discovery of the_________________.
Bacteriophage