1. 1 2. Nucleic acids and proteins in one and more dimensions

2. Protein sequence data banks 2 2. Nucleic acids and proteins in one and more dimensions

3. 3 Protein sequence data banks

4. 2. Nucleic acids and proteins in one and more dimensions 4 Protein sequence data banks

5. 2. Nucleic acids and proteins in one and more dimensions 5 Protein sequence data banks

6. 6 2. Nucleic acids and proteins in one and more dimensions Protein sequence data banks

7. 7 2. Nucleic acids and proteins in one and more dimensions

8. 8 what to do with sequences? 2. Nucleic acids and proteins in one and more dimensions

9. 9 GXXXXGK(T/S) ATP or GTP binding site protein sequence annotation what to do with sequences? 2. Nucleic acids and proteins in one and more dimensions

10. 10 2. Nucleic acids and proteins in one and more dimensions functions from nucleotide sequence protein 3D structure

11. http://en.wikipedia.org/wiki/Protein_structure 11 2. Nucleic acids and proteins in one and more dimensions

12. Proteins: different functions and architectures 12 2. Nucleic acids and proteins in one and more dimensions

13. 13 Proteins: not all structures are equally possible 2. Nucleic acids and proteins in one and more dimensions

14. Gopalasamudram Narayana Iyer Ramachandran φ ψ 14 2. Nucleic acids and proteins in one and more dimensions

15. Gopalasamudram Narayana Iyer Ramachandran φ ψ 180 -180 0 0 φ ψ 15 2. Nucleic acids and proteins in one and more dimensions

16. 16 2. Nucleic acids and proteins in one and more dimensions Gopalasamudram Narayana Iyer Ramachandran

17. 17 2. Nucleic acids and proteins in one and more dimensions

18. side chain conformation Torsion Axes and Dihedral Angles of the side chain of Lysine The sample amino acid Lysine has four torsion axes within its side chain. The torsion axes are symbolized as arrows, the dihedral angles are labeled chi1 to chi4. 18 2. Nucleic acids and proteins in one and more dimensions

19. α helix in α-helix hydrogen bonds between carbonyl i and amide i+4 19 2. Nucleic acids and proteins in one and more dimensions

20. Folding mechanism of alpha helices 20 α helix 2. Nucleic acids and proteins in one and more dimensions

21. φ ψ 180 -180 0 0 21 α helix and... 2. Nucleic acids and proteins in one and more dimensions

22. 22 β strands and β sheets 2. Nucleic acids and proteins in one and more dimensions

23. 23 β strands and β sheets 2. Nucleic acids and proteins in one and more dimensions

24. 24 β strands and β sheets 2. Nucleic acids and proteins in one and more dimensions

25. 25 β strands and β sheets 2. Nucleic acids and proteins in one and more dimensions

26. 26 filamenti β formano foglietti β 2. Nucleic acids and proteins in one and more dimensions

27. turns and loops 27 2. Nucleic acids and proteins in one and more dimensions

28. (e) 28 structural motifs or supersecondary structures 2. Nucleic acids and proteins in one and more dimensions

29. 29 protein domains 2. Nucleic acids and proteins in one and more dimensions

30. 30 protein domains Glyceraldehyde 3-Phosphate NAD Glyceraldehyde 3-Phosphate dehydrogenase 2. Nucleic acids and proteins in one and more dimensions

31. 31 protein domain assembly 2. Nucleic acids and proteins in one and more dimensions

32. Quaternary Structure heteromultimers homomultimers 32 2. Nucleic acids and proteins in one and more dimensions

33. X ray diffraction Cryo-electron microscopy Nuclear Magnetic Resonance (NMR) 33 2. Nucleic acids and proteins in one and more dimensions Guided tour of Protein Data Bank three techniques to make it growing

34. 2. Nucleic acids and proteins in one and more dimensions 34 Guided tour of Protein Data Bank

35. 2. Nucleic acids and proteins in one and more dimensions 35 Guided tour of Protein Data Bank B factor occupancy

36. 2. Nucleic acids and proteins in one and more dimensions 36

37. 2. Nucleic acids and proteins in one and more dimensions 37 https://www.youtube.com/watch?v=UHOUFJmj_fM https://www.youtube.com/watch?v=1cIE9owcy2s

38. 2. Nucleic acids and proteins in one and more dimensions 38 how to install PyMOL