1. Date of download: 2/26/2013 Copyright © 2012 American Medical Association. All rights reserved. From: Incidence of Breast Cancer With Distant Involvement Among Women in the United States, 1976 to 2009 JAMA. 2013;309(8):800-805. doi:10.1001/jama.2013.776 Increases from 1976 through 1988 in the localized disease graph were due to national implementation of screening mammography. The regressions are logarithmic, with 1990 as the starting year for localized disease among 40-year-olds to avoid the screening mammography effect during prior years. APC indicates annual percent change; SEER, Surveillance, Epidemiology, and End Results. Figure Legend :

2. Date of download: 2/26/2013 Copyright © 2012 American Medical Association. All rights reserved. From: Incidence of Breast Cancer With Distant Involvement Among Women in the United States, 1976 to 2009 JAMA. 2013;309(8):800-805. doi:10.1001/jama.2013.776 All 3 regressions are exponential. APC indicates annual percent change; SEER, Surveillance, Epidemiology, and End Results. Figure Legend :

3. Date of download: 2/26/2013 Copyright © 2012 American Medical Association. All rights reserved. From: Incidence of Breast Cancer With Distant Involvement Among Women in the United States, 1976 to 2009 JAMA. 2013;309(8):800-805. doi:10.1001/jama.2013.776 Error bars indicate 95% confidence intervals; APC, annual percent change; SEER, Surveillance, Epidemiology, and End Results. Figure Legend :