1. Cracking the NRPS Code Nick Till Computational Biology 12-15-2015

2. Proteins without Genes Tyrocidine Vancomycin

3. Nonribosomal Peptide Synthesis Taken without permission from J. Christopher Anderson

4. A-domain Recognition Site Chem. And Biol. 1999, 6, 493-505

5. A-domain Sequences

6. Machine Learning Approach

7. Information Content in 10-mers

8. Prediction Results

9. Conclusion Predictor works for about 50% of sequences picked at random IC Bar Charts show some explanation for some poor predictions A more intricate weighting function for the Hamming Distance could improve prediction power.

10. Signatures Chem. And Biol. 1999, 6, 493-505