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DNA Replication –http://www.youtube.com/watch?v=hfZ8o9D1tus (YouTube)http://www.youtube.com/watch?v=hfZ8o9D1tus Transcription & Translation –http://molo.concord.org/database/activities/273.html (FLASH)http://molo.concord.org/database/activities/273.html –What makes a firefly glow?What makes a firefly glow? –PBS: The Secret of Life (YouTube)PBS: The Secret of Life Translation –http://www.abdn.ac.uk/~clt011/flash/samples/protein.swf (FLASH)http://www.abdn.ac.uk/~clt011/flash/samples/protein.swf
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DNANucleic Acid DNA is a Nucleic Acid http://ghr.nlm.nih.gov/dynamicImages/understandGenetics/basics/chromosome_structure.jpg http://www.phoenix5.org/glossary/graphics/CellChromoDNAGene.gif
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nucleotides3 parts: --- 5 C sugar,N base &Phosphate group All nucleotides consist of 3 parts: --- 5 C sugar, N base & Phosphate group http://fig.cox.miami.edu/~cmallery/150/chemistry/sf3x6.jpg
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complementary bases (bond) Only complementary bases will pair together (i.e., form a bond) http://fig.cox.miami.edu/~cmallery/150/gene/c16x6base-pairs.jpg http://fig.cox.miami.edu/~cmallery/150/gene/16x5bc.jpg
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DNADouble Helix DNA forms a Double Helix http://test3-sftt.terc.edu/units/genes/common_content/images/s01_helix-ladder_01.gif http://www.starsandseas.com/SAS_Images/SAS_Genetics_images/DNA_images/dnamodel_1.jpg
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DNA chromatinreplication? Why does DNA need to be in the form of chromatin for replication to occur? http://www.eduvinet.de/mallig/bio/Repetito/Mitose1.html interphase chromatin This cell is in interphase. Notice the chromatin in the nucleus. prophase DNA chromosomes This cell is in prophase. The DNA has already replicated and now the chromatin is getting shorter (forming chromosomes).
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DNA replicationsemi-conservative DNA replication is semi-conservative http://www.nicerweb.com/doc/class/bio100/Locked/media/ch14/DB14050.jpg http://www.steve.gb.com/images/science/dna_replication_fork.png
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DNA Replication DNA Replication http://fig.cox.miami.edu/~cmallery/150/gene/c16x7copy-dna.jpg
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DNA vs. RNA DNA vs. RNA http://images.clinicaltools.com/images/gene/dna_versus_rna_reversed.jpg
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TRANSCRIPTION(DNA RNA) TRANSCRIPTION (DNA RNA) http://www.brooklyn.cuny.edu/bc/ahp/BioInfo/graphics/Transcription.01.GIF http://fig.cox.miami.edu/~cmallery/150/gene/dogma.htm
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CODONScodeforAmino Acids CODONS code for Amino Acids http://evolution.berkeley.edu/evosite/evo101/images/codon_GCA.gif http://coris.noaa.gov/glossary/codon_186.jpg
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The Genetic Code The Genetic Code http://fig.cox.miami.edu/~cmallery/150/gene/sf11x10.jpg
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DNA mRNA Protein http://www.iir.suite.dk/IIR/15genes/images/15DNAToProt2.gif
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TRANSLATION= proteins (polypeptides) TRANSLATION = the synthesis of proteins (polypeptides) http://mandevillehigh.stpsb.org/2005site/teacher_sites/laura_decker/dna_and_rna_diagrams_files/image008.jpg http://ghs.gresham.k12.or.us/science/ps/sci/ibbio/chem/nucleic/chpt15/tRNA.gif
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tRNAsamino acids mRNA tRNAs carry amino acids to the proper location on the mRNA strand Anticodonscomplementary codonsmRNA Anticodons are complementary to the codons of mRNA
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The Central Dogma of Molecular Genetics The Central Dogma of Molecular Genetics http://www.anselm.edu/homepage/jpitocch/genbio/transcrtransl.JPG http://www.anselm.edu/homepage/jpitocch/genbio/codonsAA.JPG
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http://library.thinkquest.org/C004535/protein_synthesis.html
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Double-strandedDNAunzip TWO… Double-stranded DNA will unzip for TWO reasons… http://www.sidwell.edu/us/science/vlb98/projects/protein/smarks/dnarepvsprosynp.gif
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GENE MUTATIONS–insertions, deletions&substitutions GENE MUTATIONS – insertions, deletions & substitutions http://fajerpc.magnet.fsu.edu/Education/2010/Lectures/26_DNA_Transcription.htm
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SICKLE-CELL ANEMIA SICKLE-CELL ANEMIA http://www.anselm.edu/homepage/jpitocch/genbio/effectsofsickle.JPG http://healthgate.partners.org/images/si55551158.jpg
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Sickle-Cell Anemia substitution(point)mutation Sickle-Cell Anemia is the result of a substitution (point) mutation http://fajerpc.magnet.fsu.edu/Education/2010/Lectures/26_DNA_Transcription.htm
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Aa x Aa Aa x Aa http://www.sciencemuseum.org.uk/exhibitions/genes/225.asp SICKLE-CELL ANEMIA
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TAY-SACHS DISEASE TAY-SACHS DISEASE http://lovequilts2005children.homestead.com/RachaeliF.html http://www.snof.org/maladies/tay.html Rachaeli F. Born: Born: October 25, 2002 Illness: Illness: Tay-Sachs Disease (terminal)
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PHENYLKETONURIA (PKU) PHENYLKETONURIA (PKU) http://www.newbornscreening.info/tools/GraphicsLib/phenylketonuria.jpg
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CYSTIC FIBROSIS (CF) CYSTIC FIBROSIS (CF) http://images.webmd.com/images/hw/media66/medical/hw/nr551844.jpg http://www.cfgenetherapy.org.uk/images/phyisiotherapy.jpg
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HUNTINGTON’S DISEASE (HD) HUNTINGTON’S DISEASE (HD) http://www.curehd.org / PLEASE HELP ME SAVE MY KIDS!!! Huntington's DiseaseHD My name is Robert Bishop. I am 43 years old and the father of five at-risk children (ages 18, 15, 12, 9, and 7). In 1998, I sold my computer software business to take up the cause of fund raising and public awareness for a terminal illness called Huntington's Disease (HD). Unless a cure is found, 2 or 3 of my children will tragically die from this disease. Each has a 50% chance of having inherited a defective gene from their first mother, Amy (who became symptomatic for HD in her mid-twenties).
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AMNIOCENTESIS AMNIOCENTESIS http://amniocentesis.upmc.com/Images/Sub/ImageAmnio.jpg
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GENETIC ENGINEERING GENETIC ENGINEERING http://floti.bell.ac.uk/mcgarvieg/Insulin.gif
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CLONING http://www.vamr.org/img/scnt_flow.jpg http://static.howstuffworks.com/gif/cloning-sheep.gif
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