1. CDRP Program Update UPMC McKeesport Program Steering Committee RTOG Meeting Toronto, Canada June 23 rd, 2006

2. Overview Multi-modality & RT trials clinical trials UPMC Cancer Center Initiatives Clinical trials accrual Navigators update TELESYNERGY update Mentors update

3. Multi-modality Clinical Trials Tracking Mechanisms UPMC Health System sites (UPMC McKeesport, New Castle, Murtha Cancer Pavilion) Scan UPMC Cancer Centers protocol listings on monthly basis to identify service area patients Navigators will work with on-site department nurses and med-onc protocol nurses to identify patients as they are put on trials Mercy Cancer Institute No multi-modality trials offered Somerset Oncology Center No trials offered at this site to date Remains a challenge 2 0 to infrastructure but progress being made

4. UPMC Cancer Centers Initiative African American Cancer Care Partnership (AACCP) $750,000 provided by UPMC Health System 4 UPMC sites designated – including UPMC McKeesport Provides payment for initial consult for newly diagnosed breast, colorectal, lung or prostate cancer On consult patients are evaluated for clinical trials as well as needs for resource programs such as Patient Navigator To date 8 of 38 patients at the four sites have been entered on clinical trials!!

5. All Clinical Trials Distribution by ethnicity (A/A = 14%) May 2006

6. All Clinical Trials Comparison of multi-modality to RT enrollment

7. All Clinical Trials By age: A/A (2004 – 2005)

8. All Clinical Trials by gender – May 2006

9. Other Clinical Trials Patient Navigator Total patients: 195 African American: 48 (25% over all 5 sites) Hispanic: 2 Asian: 1 ASTRO-Sponsored Study How Can Radiation Oncologists Better Serve Their Patients? A Randomized Study to Determine Whether Radiation Oncologists Can Improve Patient Satisfaction by Attempting to Meet Their Patients’ Preferences (anticipated accrual = 500)

10. Patient Navigator May 2006 14% A/A18% A/A32% A/A

11. Evaluation of the Tailored Patient Navigator Programs for the Underserved Populations with Cancer is a “process” evaluation of a PNP study has enrolled 44 African Americans and 130 non-African Americans from the target areas who have a confirmed diagnosis of cancer 174 participants enrolled from January 2005 through May 2006, 32.1% of enrollees within the urban facility were African Americans versus 14.7% at the non-urban facility

14. TELESYNERGY® Continue to formulate ways to integrate its use with mentors, esp. for professional development System is integral to tumor board @ McKeesport Streaming video capabilities allows for wider audience participation with teleconferencing Demo at this meeting

15. Abstracts Publications Abstracts accepted for ASTRO 2006 A Comprehensive Outcomes-Based Planning and Evaluation Program for Implementing TELESYNERGY® and Other Videoconferencing Approaches in Radiation Oncology –Ed Ricci, PhD Analysis of “Best Practice” Treatment Patterns for a Radiation Oncology Community Outreach Group (ROCOG) Engaged in Cancer Disparities Outcome-Julian Proctor, MD Cancer Health Disparities symposium 2006 UPMC McKeesport Radiation Oncology Minorities Community Outreach Group- Dwight Heron, MD International Intercultural Council 2006 Breaking Barriers: A Navigator Program of Cancer Care for the Underserved Populations-Karen Schwaderer, RN Academy Health Symposium Evaluation of the Tailored Patient Navigator Programs for the Underserved Populations with Cancer-Cho Cho Lin, PhD American Telemedicine Association A Multi-institutional Mobility Initiative for TELESYNERGY® and other Teleconferencing Systems”-Larry Schenken, PhD 4 Manuscripts in preparation at various stages