1. Cell Division— Mitosis Notes

2. Why do Cells Need to Divide? Transport of materials in and out of the cell is MUCH FASTER over short distances. DNA codes the proteins our cells need to survive. The larger the cell, the more protein it would need and DNA could not keep up! Surface Area to Volume Ratio – the larger the cell, the more volume it has. More is needed and more waste is produced. It would need more surface area than the membrane could provide.

3.   Living things grow by producing more cells, NOT because each cell increases in size Why do cells need to divide?

4. Cell Division — process by which a cell divides into 2 new cells

5.  Remember from the cell theory that all cells come from preexisting cells, so genetic information has to be passed from one generation to the next. Cell Reproduction

6.  Genetic information is contained in DNA – deoxyribonucleic acid which is in the nucleus of a cell.  DNA exists in the nucleus as long, threadlike strands called chromatin.  When a cell is going to divide and produce more cells, the chromatin winds up into a double, coiled structure called a chromosome. Cell Reproduction

8.  All cells of the body EXCEPT the sex cells are called somatic cells.  Blood cells, nerve cells, skin cells, etc.  New somatic cells are made when one parent cell divides into two identical daughter cells Cell Division

9.  The Cell Cycle: The process somatic cells go through in order to grow and reproduce  The cell cycle is divided into two main parts:  Interphase  Mitosis (M Phase) Cell Division

11.  Interphase– this is a time of growth and a time when DNA is replicated (a copy is made) inside the nucleus of the cell Interphase

12.  G1 Phase – G is for GROWTH! The cell is growing and making proteins  S Phase – S is for SYNTHESIS (making something). This is when the DNA is replicated and an identical set of chromosomes is made  G2 Phase – G is for GROWTH. The cell continues to grow and is getting ready for mitosis (division) Interphase

14.  Mitosis is when the nucleus divides  The second part of the cell cycle is mitosis and cytokinesis.  Cytokinesis is when the entire cell divides Mitosis

15.  Mitosis is divided into 4 phases:  Prophase  Metaphase  Anaphase  Telephase Mitosis

16.  The chromatin coils up tightly, gets shorter and thicker, and can be seen in the nucleus.  The chromatin is lined up in a way that two sister chromatids are held together at a middle point called a centromere. Each sister is a duplicate of the other (this was done in S phase). Prophase

18.  The nuclear membrane disintegrates and a spindle starts to form.  Spindle – Microtubules that line up in a spindle form in the cell to help division Prophase http://www.ptbeach.com/site/default.aspx?PageType=3&ModuleInstanceID=444&Vi ewID=7b97f7ed-8e5e-4120-848f- a8b4987d588f&RenderLoc=0&FlexDataID=347&PageID=907

20.  Chromatids line up in the MIDDLE.  They attach to the spindle at the centromere in the middle of the nucleus (equator) Metaphase https://commons.wikimedia.org/wiki/File:Mitotic_Metaphase.svg

21.  Chromatids are pulled apart by the spindle. Each chromatid is now its own chromosome Anaphase http://www.proprofs.com/flashcards/story.php?title=pratical- 1_1

22.  The chromosomes reach opposite ends of the cell and start to unwind.  Spindle disappears  Two new nuclear membranes form around each set of chromosomes to form two new nuclei Telophase

23. Telophase http://home.apu.edu/~jsimons/Bio101/genetics.htm

24.  The cytoplasm divides during cytokinesis Cytokinesis http://www.celldynamics.org/celldynamics/research/cytokinesis/inde x.html

25.  In plant cells, a cell plate forms between the two nuclei and grows out to the edges, dividing the cell in half.  In the plant cell, a new cell membrane will form around each cell and a cell wall forms around the outside. Plant vs Animal

27. InterphaseM Phase (Mitotic) G1-GrowthProphase – Chromatin Condenses S-Synthesis-DNA Replication Metaphase – Chromatids line up in the middle G2 - GrowthAnaphase – Chromatids separate Telophase – New nuclear membranes

28. Identify the Following Stages of Mitosis!

38. What is the longest part of the cell cycle?

39. Interphase

40. In which part of interphase are the chromosomes replicated?

41. S Phase

42. During what part of interphase does the cell grow and prepare for mitosis?

43. G2

44. What is the division of the nucleus called?

45. Mitosis

46. What is the division of the entire cell called?

47. Cytokinesis

48. If you are observing a cell and notice that the chromosomes appear to be lined up in the middle of the nucleus, what stage of mitosis are you observing?

49. Metaphase

50. If it looks as though the cell you see through the microscope has two nuclei, what stage of mitosis are you observing?

51. Telophase

52. A cell plate is forming in one of the cells that you are observing. Which of the following type of cells could you be viewing?

53. a. Human skin cells b. Root tip cells c. A fly’s eye d. bristles of an earthworm

54. Root tip cells!

55. In which of the following circumstances would cells NOT divide by the process of mitosis?

56. a. Repairing a cut b. Adding cells for an infant to grow c. Creating sex cells d. Replacing old skin cells

57. Creating sex cells

58. How many times do chromosomes separate during the process of mitosis?

59. One

60. http://v7.k12.com/sample_lessons/activities /images/swfs/9-12/ObservingMitosis.swf