1. Training for rotavirus vaccine introduction Module 1 Introduction to rotavirus disease and vaccine

2. Introduction to rotavirus disease and vaccine, Module 1 | 31 January 2016 2 |2 | Learning objectives At the end of the module, the participant will be able to: –Describe the main characteristics of rotavirus disease –Present prevention methods against rotavirus disease Duration –15’

3. Introduction to rotavirus disease and vaccine, Module 1 | 31 January 2016 3 |3 | What are the signs and symptoms of rotavirus? 2 2 How is rotavirus spread? 3 3 Who is most at risk? 4 4 Key issues What are rotavirus prevention strategies? 5 5 What is rotavirus disease? 1 1

4. Introduction to rotavirus disease and vaccine, Module 1 | 31 January 2016 4 |4 | Rotavirus disease is a diarrheal disease caused by a virus called rotavirus The name rotavirus comes from the wheel-like appearance of the virus under the microscope Rotavirus is a virus that infects the intestines Rotavirus is the most common cause of severe diarrheal disease in infants and young children worldwide Rotavirus is not the only cause of diarrhea, several other agents may also cause diarrhea What is rotavirus disease?

5. Introduction to rotavirus disease and vaccine, Module 1 | 31 January 2016 5 |5 | Three main symptoms of rotavirus infection: –Fever –Vomiting –Watery diarrhea Abdominal pain may also occur Diarrhea usually stops after 3 to 7 days Young children can become dehydrated, requiring urgent treatment What are the signs and symptoms of rotavirus infection?

6. Introduction to rotavirus disease and vaccine, Module 1 | 31 January 2016 6 |6 | Confirmation of a diarrheal illness such as rotavirus requires laboratory testing Strains of rotavirus may be further characterized by special testing with enzyme immunoassay or polymerase chain reaction –Such testing is not commonly available or necessary How is rotavirus disease diagnosed?

7. Introduction to rotavirus disease and vaccine, Module 1 | 31 January 2016 7 |7 | Rotavirus infection is highly contagious Rotavirus spread by fecal-oral route –The primary mode of transmission of rotavirus is the passage of the virus in stool to the mouth of another child How does rotavirus spread?

8. Introduction to rotavirus disease and vaccine, Module 1 | 31 January 2016 8 |8 | Infants after the age of 3 months –Low to no immunity –Vulnerable to dehydration Older children if they are immunocompromised Who is most at risk in the population? Baby > 3 months Risk of disease Immuno- compromised Children Adults Older people Population

9. Introduction to rotavirus disease and vaccine, Module 1 | 31 January 2016 9 |9 | What can be done to prevent rotavirus and diarrheal disease?

10. Introduction to rotavirus disease and vaccine, Module 1 | 31 January 2016 10 | Is there a vaccine against rotavirus? Currently there are 2 rotavirus vaccines: –RotaTeq TM –Rotarix TM Main characteristics –Both are highly effective and safe –Both protect against severe forms of rotavirus disease –Both do not protect against diarrhea caused by other agents than rotavirus

11. Introduction to rotavirus disease and vaccine, Module 1 | 31 January 2016 11 | Our country is about to introduce Rotarix TM Next modules of this training will explain how to: Store the vaccine Determine vaccine eligibility Administer the vaccine Record the vaccine Monitor adverse events following immunization (AEFIs) Communicate with caretakers about the vaccine Rotarix TM

12. Introduction to rotavirus disease and vaccine, Module 1 | 31 January 2016 12 | End of module Thank you for your attention!