1. KEY CONCEPT DNA replication copies the genetic information of a cell.

2. In replication, the DNA is copied during the cell cycle
DNA is replicated during the S (synthesis) stage of interphase
Overview:
A single strand of DNA serves as a template for a new strand.
The rules of base pairing direct replication.
A pairs with T
C pairs with G
Each body cell gets a complete set of identical DNA.

3. Proteins carry out the process of replication.
DNA serves only as a template…enzymes and other proteins do the actual work of replication.
1. Enzymes unzip the double helix in two directions at the same time.
2. Free-floating nucleotides pair with the exposed bases on the template strand (and they form hydrogen bonds here).
nucleotide
The DNA molecule unzips in both directions. 2.
1. Sugar Phosphate Backbone

4. 3. DNA polymerase enzymes bond the new nucleotides together to form the double helix.
new strand
nucleotide 2. 4. 3.

5. DNA replication is semiconservative.
The end result:
4. Two new molecules of DNA identical to the original molecule result; each with an original and new strand.
DNA replication is semiconservative.
original strand
new strand
Two molecules of DNA

6. Replication is fast and accurate.
DNA replication starts at many points in eukaryotic chromosomes.
There are many origins of replication in eukaryotic chromosomes.
DNA polymerases can find and correct errors.