1. The Impact of For-Profit Hospital Status on the Care and Outcomes of Patients with NSTEMI: Results From CRUSADE Bimal R. Shah, MD, Seth W. Glickman, MD, MBA, Li Liang, PhD, W. Brian Gibler, MD, E. Magnus Ohman, MD, Charles V. Pollack Jr., MA, MD, Matthew T. Roe, MD, MHS, Eric D. Peterson, MD, MPH Shah, BR et al. J Am Coll Cardiol 2007; 50:1462-8.

2. BACKGROUND n We compared care processes and outcomes among patients with non-ST-segment elevation myocardial infarction (NSTEMI) between for-profit and non-profit hospitals. n While for-profit hospitals potentially have financial incentives to selectively care for younger, healthier patients, perform highly reimbursed procedures, reduce costs by limiting access to expensive medications, and encourage shorter inpatient length of stay, there are limited data available to investigate these issues objectively.

3. Shah, BR et al. J Am Coll Cardiol 2007; 50:1462-8. METHODS n Using data from the CRUSADE initiative, we investigated whether for-profit status influenced hospitals’ patient case mix, care, or outcomes among 145,357 patients with NSTEMI treated between January 1, 2001 and December 31, 2005 at 532 U.S. hospitals. n Impact of for-profit status on care and outcomes was analyzed overall and after adjustment for clinical and facility factors using generalized estimating equations regression modeling.

4. Shah, BR et al. J Am Coll Cardiol 2007; 50:1462-8. RESULTS: Patient Characteristics Data are presented as percentages except as indicated. *Presented as mean±standard deviation. † Known serum creatinine >2.0 mg/dL, calculated creatinine clearance <30 mL/min, or need for renal dialysis. BMI = body mass index; HMO = health maintenance organization; VAMC = Veterans Administration Medical Center; CAD = coronary artery disease; MI = myocardial infarction; PCI = percutaneous coronary intervention; CABG = coronary artery bypass graft; CHF = congestive heart failure.

5. Shah, BR et al. J Am Coll Cardiol 2007; 50:1462-8. RESULTS: Hospital Characteristics Data are presented as percentages except as indicated. *Membership in Council of Teaching Hospitals. † Presented as mean±standard deviation. PCI = percutaneous coronary intervention

6. Shah, BR et al. J Am Coll Cardiol 2007; 50:1462-8. RESULTS: No difference in in-hospital therapy use Data are presented as percentages except as indicated. OR = odds ratio; UFH = unfractionated heparin; LMWH = low molecular weight heparin; GP = glycoprotein; PCI = percutaneous coronary intervention; CABG = coronary artery bypass graft.

7. Shah, BR et al. J Am Coll Cardiol 2007; 50:1462-8. RESULTS: Similar rates of discharge therapy use Data are presented as percentages except as indicated. ACE = angiotensin converting enzyme.

8. Shah, BR et al. J Am Coll Cardiol 2007; 50:1462-8. RESULTS: Similar in-hospital outcomes Data are presented as percentages except as indicated. OR = odds ratio; MI = myocardial infarction; RBC = red blood cell; LOS = length of stay. *In patients not receiving coronary artery bypass graft surgery. †Major Bleeding is as defined as: 1) absolute hematocrit (HCT) drop of ≥12% (baseline HCT - nadir HCT ≥12%); 2) intracranial hemorrhage stroke; 3) retroperitoneal witnessed bleeding event; 4) baseline HCT ≥28% and RBC transfusion; 5) baseline HCT <28% and RBC transfusion and witnessed bleeding event. ‡Log transformation of adjusted LOS reported.

9. Shah, BR et al. J Am Coll Cardiol 2007; 50:1462-8. CONCLUSIONS n We found no difference in adjusted in-hospital outcomes for patients with NSTEMI at for-profit hospitals compared to non-profit hospitals. n Despite organizational differences that may exist in fiscal strategy and resource allocations, both hospital types were also similar in guideline-based therapy and procedure utilization.