1. DNA Replication Notes

2. DNA Replication DNA must be copied DNA must be copied The DNA molecule produces 2 IDENTICAL new complementary strands following the rules of base pairing: The DNA molecule produces 2 IDENTICAL new complementary strands following the rules of base pairing: A-T, G-C Each strand of the original DNA serves as a template for the new strand See p. 298Each strand of the original DNA serves as a template for the new strand See p. 298

3. DNA Replication Semiconservative Model: Semiconservative Model: Watson and Crick showed: 1.Watson and Crick showed: the two strands of the parental molecule separate, and each functions as a template for synthesis of a new complementary strand.. Parental DNA DNA Template New DNA

4. (1961) Watson & Crick proposed… …DNA controlled cell function by serving as a template for PROTEIN structure. …DNA controlled cell function by serving as a template for PROTEIN structure. 3 Nucleotides = a triplet or CODON 3 Nucleotides = a triplet or CODON (which code for a specific AMINO ACID) See p.303 AMINO ACIDS are the building blocks of proteins. AMINO ACIDS are the building blocks of proteins.

5. DNA Transcription DNA can “unzip” itself and RNA nucleotides match up to the DNA strand. DNA can “unzip” itself and RNA nucleotides match up to the DNA strand. Both DNA & RNA are formed from NUCLEOTIDES and are called NUCLEIC acids. Both DNA & RNA are formed from NUCLEOTIDES and are called NUCLEIC acids. See p.301

6. DNA Translation The cell uses information from “messenger” RNA to produce proteins The cell uses information from “messenger” RNA to produce proteins See p.304-305 We will discuss details of this on a later date

7. AMAZING DNA FACTS… DNA from a single human cell extends in a single thread for almost 2 meters long!!! DNA from a single human cell extends in a single thread for almost 2 meters long!!! It contains information equal to some 600,000 printed pages of 500 words each!!! It contains information equal to some 600,000 printed pages of 500 words each!!! (a library of about 1,000 books)