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VEGF and the Fab fragment of a humanized neutralizing antibody: crystal structure of the complex at 2.4 å resolution and mutational analysis of the interface.

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Presentation on theme: "VEGF and the Fab fragment of a humanized neutralizing antibody: crystal structure of the complex at 2.4 å resolution and mutational analysis of the interface."— Presentation transcript:

1 VEGF and the Fab fragment of a humanized neutralizing antibody: crystal structure of the complex at 2.4 å resolution and mutational analysis of the interface Yves A Muller, Yvonne Chen, Hans W Christinger, Bing Li, Brian C Cunningham, Henry B Lowman, Abraham M de Vos Structure Volume 6, Issue 9, Pages 1153-1167 (September 1998) DOI: 10.1016/S0969-2126(98)00116-6

2 Figure 1 Structure 1998 6, 1153-1167DOI: (10.1016/S0969-2126(98)00116-6)

3 Figure 2 Structure 1998 6, 1153-1167DOI: (10.1016/S0969-2126(98)00116-6)

4 Figure 3 Structure 1998 6, 1153-1167DOI: (10.1016/S0969-2126(98)00116-6)

5 Figure 4 Structure 1998 6, 1153-1167DOI: (10.1016/S0969-2126(98)00116-6)

6 Figure 5 Structure 1998 6, 1153-1167DOI: (10.1016/S0969-2126(98)00116-6)

7 Figure 6 Structure 1998 6, 1153-1167DOI: (10.1016/S0969-2126(98)00116-6)

8 Figure 7 Structure 1998 6, 1153-1167DOI: (10.1016/S0969-2126(98)00116-6)


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