1. © Cancer Research UK 2005 Registered charity number 1089464 Oral Cancer The statistics in this presentation are based on the Oral CancerStats report published in 2007. However, the incidence, mortality and survival statistics have been updated to reflect the latest available data. For more information about UK cancer statistics please contact stats.team@cancer.org.uk or visit http://info.cancerresearchuk.org/cancerstats stats.team@cancer.org.uk http://info.cancerresearchuk.org/cancerstats

2. © Cancer Research UK 2005 Registered charity number 1089464 Table One: Numbers of new cases of oral cancer in the UK 2006 EnglandWalesScotlandN.IrelandUK Cases Males2,7662114541093,540 Females1,433105195521,785 Persons4,1993166491615,325 Crude rate per 100,000 population Males11.114.618.412.811.9 Females5.56.97.45.95.8 Persons8.310.712.79.28.8 Age-standardised rate (European) per 100,000 population Males10.112.516.012.410.8 95% CI9.710.410.814.214.517.410.114.710.411.1 Females4.35.15.55.04.5 95% CI4.14.54.16.04.76.33.66.34.34.7 Persons7.18.710.48.47.5 95% CI6.97.37.79.6 11.27.19.77.37.7

3. © Cancer Research UK 2005 Registered charity number 1089464 Figure One: Number of new cases and rates by age, oral cancer, UK, 2006

4. © Cancer Research UK 2005 Registered charity number 1089464 Figure Two: World age standardised* male incidence rates for cancer of the oral cavity and cancers of the pharynx excluding the nasopharynx in selected countries of the world, 2002 estimates * to the European standard population

5. © Cancer Research UK 2005 Registered charity number 1089464 Figure Three: European age standardised* incidence rates, by sex, oral and pharyngeal cancer, EU countries, 2002 estimates * to the European standard population

6. © Cancer Research UK 2005 Registered charity number 1089464 Figure Four: Age standardised* (European) incidence rates, by sex, oral cancer, Great Britain, 1975-2006 * to the European standard population

7. © Cancer Research UK 2005 Registered charity number 1089464 Figure Five: Age-specific incidence rates, male oral cancer, Great Britain, 1975-2006

8. © Cancer Research UK 2005 Registered charity number 1089464 Figure Seven: Percentage of South Asians in the UK that use any form of chewing tobacco, 2004

9. © Cancer Research UK 2005 Registered charity number 1089464 Figure Eight: Relative risk of oral/pharyngeal cancer in males by alcohol/tobacco consumption using US measures

10. © Cancer Research UK 2005 Registered charity number 1089464 Figure Nine:Alcohol consumption in the UK 1900-2000 per capita consumption of 100 per cent alcohol

11. © Cancer Research UK 2005 Registered charity number 1089464 Table Three: Possible symptoms of oral cancer A mouth sore/ulcer that fails to heal or that bleeds easily All red or red and white patches in the mouth that will not go away A lump or thickening in the mouth, tongue or throat Difficulty chewing or swallowing food New persistant pain

12. © Cancer Research UK 2005 Registered charity number 1089464 Table Four: Stage and 2 year crude survival, cancers of oral cavity and pharynx, South and West of England, 1996-2000 Oral cavity2-year crudePharynx2-year crude No. of casessurvival (CI)No. of casessurvival (CI) % % All cases41162.0 (57.3-66.7)27950.9 (45.0-56.8) I Early disease2187.5 (80.6-94.4)677.8 (58.6-97.0) II Locally advanced1768.6 (57.6-79.6)1452.6 (36.7-68.5) III Tumour in lymph nodes1552.5 (40.0-65.0)2249.2 (36.7-61.7) IV Metastatic3646.0 (38.0-54.0)4846.6 (38.2-55.0) Unknown1168.2 (54.5-81.9)1055.2 (37.2-73.2)

13. © Cancer Research UK 2005 Registered charity number 1089464 Figure Ten: Comparison of age standardised* 5 year relative survival rates for patients diagnosed in 1991-1995 and 1996-1999, England and Wales. * to the European standard population

14. © Cancer Research UK 2005 Registered charity number 1089464 Figure Eleven: Comparison of age standardised* 5 year relative survival rates for patients diagnosed in 1991-1995 and 1996-1999, England and Wales. * to the European standard population

15. © Cancer Research UK 2005 Registered charity number 1089464 Figure Twelve: Five year relative survival by age, cancers of the oral cavity, oropharynx and tongue, 1996-99 patients, England and Wales

16. © Cancer Research UK 2005 Registered charity number 1089464 Table Five: Comparison of survival in affluent and deprived patients, 1986-90, England and Wales Five year survival % for the most affluent Five year survival % for the most deprived Gap between most affluent and most deprived Tongue 50.4 34.1 -16.3 Oropharynx 41.9 29.9 -12 Oral cavity 53.9 42.3 -11.6

17. © Cancer Research UK 2005 Registered charity number 1089464 Table Six: Numbers and rates of death, oral cancer, UK, by country, 2007 EnglandWalesScotlandN.IrelandUK Deaths Males98378160381,259 Females454398910592 Persons1,437117249481,851 Crude rate per 100,000 population Males3.95.46.44.44.2 Females1.72.63.31.11.9 Persons2.83.94.82.73.0 Age-standardised rate (European) per 100,000 population Males3.44.35.34.33.7 CI 95%3.23.63.45.34.56.12.95.73.53.9 Females1.21.72.30.91.3 CI 95%1.11.31.22.31.82.80.41.51.21.4 Persons2.32.93.72.52.4 CI 95%2.12.4 3.53.24.21.83.22.32.5

18. © Cancer Research UK 2005 Registered charity number 1089464 Figure Thirteen: Numbers of deaths and age-specific mortality rates by sex, oral cancer, UK 2007

19. © Cancer Research UK 2005 Registered charity number 1089464 Figure Fourteen: Trends in mortality for oral cancer in UK males 1971-2007 by age