1. AUC - Past & Present Stephen Harding

2. Thé Svedberg 1884-1971

3. Svedberg oil-turbine ultracentrifuge

4. “Evolution” of the AUC Numbers of papers in the Biochemical Journal, per annum

5. 1920’s: “Thé: I see a new dawn! ” Svedberg & Nichols: oil turbine u/c Optical system Rinde: sector shape cell Hemoglobin - Svedberg & Fåhraeus

6. 1926: 1 st AUC paper on sedimentation equilibrium

8. 1930’s: “Proteins are molecules” Philpott/Svensson Schlieren optics Proteins as molecules Concept of subunits Perrin: Frictional ratio calculations and shapes of molecules: TMV

10. 1930’s: “Proteins are molecules” Philpott/Svensson Schlieren optics Proteins as molecules Concept of subunits Perrin: Frictional ratio calculations and shapes of molecules: TMV

11. 1930’s: “Proteins are molecules” Philpott/Svensson Schlieren optics Proteins as molecules Concept of subunits Perrin: Frictional ratio calculations and shapes of molecules: TMV

12. 1948: Discovery of electricity is taken into account Spinco Model E (Pickels) Beckman Model E (Pickels)

14. 1948: Analysis of Mixtures A.G. “Sandy” Ogston

15. “Evolution” of the AUC Numbers of papers in the Biochemical Journal

16. YphantisSchachman Williams van Holde

17. “Evolution” of the AUC Numbers of papers in the Biochemical Journal

18. 1980’s: “ Take our advice and switch to more useful techniques like NMR” “Advice” from the Biochemical Journal Garcia de la Torre: bead models National Centres in the USA and UK 1989 – news of another “new dawn”

20. April 1991