1. Yvette Garcia, PharmD, BCPS 1 st Year Executive Administration Program

2. To evaluate whether a pharmacist-driven intervention program affects total pharmacy savings Within the past 2 years an antibiotic stewardship program was implemented at Rio Grande Regional Hospital Pharmacists are required to make and document medication interventions on a daily basis

3. Monthly total numbers of antibiotic interventions and defined daily doses (DDD) per 1,000 adjusted-patient days (APD) Hypothesis Total savings=$6984.26 +$113.06 X1 + $5.29 X2 + ε X1: antibiotic interventions X2: DDD/1K APD

6. 70% of variation in savings can be explained by variation in antibiotic interventions and DDD/1 K APD Regression Statistics Multiple R0.70 R Square0.49 Adjusted R Square0.44 Standard Error2497.50 Observations26

7. On average each patient has a total savings of $6,984.26 with an additional savings of $113.06 per antibiotic intervention and $5.29 per DDD/1K APD ANOVA dfSSMSFSignificance F Regression2136090232.6068045116.3010.910.00 Residual23143463009.446237522.15 Total25279553242.04 Coefficients Standard Errort StatP-valueLower 95%Upper 95% Intercept6984.267306.920.960.35-8131.2622099.79 Antibiotic Interventions113.0624.594.600.0062.19163.92 DDD/1 K APD5.299.850.540.60-15.0825.67

8. Antibiotic interventions are a significant determinant of total savings To increase total savings pharmacist should continue to evaluate patients for antibiotic interventions