Presentation is loading. Please wait.

Presentation is loading. Please wait.

Recent advances in the monitoring and management of diabetic ketoacidosis by T.M. Wallace, and D.R. Matthews QJM Volume 97(12):773-780 November 29, 2004.

Similar presentations


Presentation on theme: "Recent advances in the monitoring and management of diabetic ketoacidosis by T.M. Wallace, and D.R. Matthews QJM Volume 97(12):773-780 November 29, 2004."— Presentation transcript:

1 Recent advances in the monitoring and management of diabetic ketoacidosis by T.M. Wallace, and D.R. Matthews QJM Volume 97(12):773-780 November 29, 2004 QJM vol. 97 no. 12 © Association of Physicians 2004; all rights reserved.

2 (a) Increased lipolysis results in the production of acetylCoA from fatty acids which acts as the substrate for hepatic synthesis of ketone bodies (acetoacetate, beta-hydroxybutyrate and acetone). T.M. Wallace, and D.R. Matthews QJM 2004;97:773-780 QJM vol. 97 no. 12 © Association of Physicians 2004; all rights reserved.

3 Glucose and β-OHB profiles in two patients admitted with DKA. There is an initial reduction in β- OHB and glucose with treatment. T.M. Wallace, and D.R. Matthews QJM 2004;97:773-780 QJM vol. 97 no. 12 © Association of Physicians 2004; all rights reserved.

4 The time course for blood glucose (squares), β-hydroxybutyrate (β-OHB, diamonds) and bicarbonate (triangles) in hours from initiation of treatment. T.M. Wallace, and D.R. Matthews QJM 2004;97:773-780 QJM vol. 97 no. 12 © Association of Physicians 2004; all rights reserved.

5 Guidelines for the use of the ketone meter in out-patients. T.M. Wallace, and D.R. Matthews QJM 2004;97:773-780 QJM vol. 97 no. 12 © Association of Physicians 2004; all rights reserved.


Download ppt "Recent advances in the monitoring and management of diabetic ketoacidosis by T.M. Wallace, and D.R. Matthews QJM Volume 97(12):773-780 November 29, 2004."

Similar presentations


Ads by Google