1. The Cochrane Collaboration and the Cochrane Library South Asian Cochrane Network Workshop, IUB, Dhaka 4 May 2007 Andy Oxman Norwegian Knowledge Centre for the Health Services

2. What is a systematic review? Establish objectives + selection criteria Search for eligible studies Apply selection criteria Assess study quality + assemble data Analyse results using meta-analysis, if appropriate and possible Prepare report Keep it up to date

3. Questions about what a systematic review is?

4. The Cochrane Collaboration An international organisation that aims to help people make well-informed decisions about healthcare by preparing, maintaining and promoting the accessibility of systematic reviews of the effects of healthcare interventions.

5. Principles Collaboration Building on enthusiasm of individuals Avoiding duplication Minimising bias Keeping up to date Striving for relevance Promoting access Ensuring quality Ensuring continuity Enabling wide participation

6. A brief history 1948 Streptomycin treatment of pulmonary tuberculosis: a Medical Research Council investigation. BMJ 1948; ii:769-82. 1972 Cochrane AL. Effectiveness and Efficiency. Random Reflections on Health Services 1974 Oxford Database of Perinatal Trials (ODPT) conceived 1989 ODPT first published

7. The Cochrane Collaboration 1992 UK Cochrane Centre 1993 Cochrane Collaboration 1994Cochrane Database of Systematic Reviews 1996 Cochrane Library

8. DatabaseRecords The Cochrane Database of Systematic Reviews (Cochrane Reviews) Complete reviews New Updated Protocols 4410 2785 111 58 1625 Database of Abstracts of Reviews of Effects (Other Reviews)5574 The Cochrane Central Register of Controlled Trials (Clinical Trials)477942 The Cochrane Database of Methodology Reviews (Methods Reviews)23 The Cochrane Methodology Register (Methods Studies)8408 Health Technology Assessment Database (Technology Assessments)6011 NHS Economic Evaluation Database (Economic Evaluations)18852 About The Cochrane Collaboration and the Cochrane Review Groups (Cochrane Groups) 91

9. Cochrane Reviews

10. Access National licenses –Australia –Denmark –England –Finland –India –Ireland –New Zealand –Norway –Scotland –Sweden –Wales Low–Income Countries –Health InterNetwork Access to Research Initiative (HINARI) –International Network for the Availability of Scientific Publication's (INASP) –South African Cochrane Centre sponsorship –Latin America, the Caribbean (BIREME)

11. About the Cochrane Collaboration

12. Review Groups

17. Centres

18. Centres

19. Centres

20. Centres

21. Fields (Networks) & Methods Groups

22. www.cochrane.org

23. Questions about the Cochrane Collaboration or the Cochrane Library?

24. Two perspectives of the Cochrane Collaboration

26. “Massive data analysis can reduce the chaos of medical practice.” Richard Peto, Oxford