1. www.wemove.org Essential Tremor Slide Library Version 1.0 - All Contents Copyright © WE MOVE 2001 Essential Tremor and Parkinson’s Disease Part 5 of 7

2. ET: Overlap with PD ET and PD are among the most common movement disorders ET is considered the most prevalent movement disorder in the U.S. ET/PD: Pathophysiological relationship not established 2% to 19% of ET patients report parkinsonism www.wemove.org

3. ET: Overlap with PD 10% of ET patients have a positive family history of PD PD more common in ET and kindreds than otherwise expected: Geraghty and Jankovic (1985). Lang (1986). Koller (1994). ET patient may develop striatonigral deficiency: Lee (1999). Farrer et al. (1999). www.wemove.org

4. ET and PD: Epidemiologic Investigations Possible association: –Hornabrook and Nagurney (1976) –Jankovic and Geraghty (1985) –Jankovic et al. (1995) www.wemove.org

5. PD and ET www.wemove.org

6. PD and ET www.wemove.org

7. Tremor Due to PD and ET www.wemove.org