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A 30-year male with cognitive decline and unsteady gait Teaching NeuroImages Neurology Resident and Fellow Section © 2013 American Academy of Neurology.

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Presentation on theme: "A 30-year male with cognitive decline and unsteady gait Teaching NeuroImages Neurology Resident and Fellow Section © 2013 American Academy of Neurology."— Presentation transcript:

1 A 30-year male with cognitive decline and unsteady gait Teaching NeuroImages Neurology Resident and Fellow Section © 2013 American Academy of Neurology

2 Vignette A 30-year old male with history of bipolar disease presented with 6 months of cognitive decline, unsteady gait, urinary retention, and bilateral upper extremity tremors Ramanathan et al.

3 Imaging A D C B Ramanathan et al.

4 Diffuse Cerebral Neurosarcoidosis mimicking Gliomatosis Cerebri Neurosarcoidosis can mimic infection (viral, tuberculosis, or cryptococcus), toxic leukoencephalopathy & malignancies like gliomatosis cerebri or angiocentric lymphoma. MRI in neurosarcoidosis often reveals enhancing periventricular white matter lesions, in this case mimicking diffuse gliomatosis cerebri 1,2. The patient responded well to high dose steroids and intravenous cyclophosphamide. Ramanathan et al

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