1. Practice Quiz Endocrine Physiology Physiology Fall 2009

2. 1. An individual suffering from primary hyperthyroidism would exhibit which of the following symptoms? a. increased T3 secretion b. Weight loss c. Hyperpigmentation d. hypothermia e. elevated levels of TSH

3. 2. A fall (decrease) in plasma calcium concentration should result in: a.Increased parathyroid hormone secretion b.More conversion of Vitamin D to the active hormone in the kidney c.More excretion of Ca++ in urine d.Decreased resorption of bones by osteoclasts

4. 3. Which of the following is released from the anterior pituitary gland? a.Leutinizing hormone b.Prolactin c.Oxytocin d.Thyroid stimulating hormone e.Dopamine f.Vasopressin g.Gonadotropin Releasing Hormone

5. 4. Which of the following lead(s) to an increase in cortisol? a.Increased adrenocortotropic hormone b.Decreased corticotropin releasing hormone c.Increased thyroid stimulating hormone d.Prolonged exposure to cold e.Psychological anxiety f.Increased levels of Vasopressin g.Cytokines from cells of the immune system

6. 5. Cell of the adrenal cortex secrete more aldosterone in response to which of the following ? a.Increasing plasma concentration of Na+ b.Increasing plasma concentration of Ka+ c.Angiotensinogen d.Angiotensin I e.Angiontensin II f.Renin g.ACTH

7. 6. Addison’s Disease is characterized by: a.Increased cortisol b.Disturbances in plasma electrolytes c.Decreased adrenocorticotropic hormone secretion d.Less than normal aldosterone secretion e.Increased sodium excretion in the urine f.Patchy hyperpigmentation of skin

8. 7. Which of the following hormones travels in the blood bound to carrier proteins? a.Oxytocin b.T4 c.Aldosterone d.Leutinizing hormone e.Estradiol f.TSH g.EPI

9. 8. Gonadotropin releasing hormone is synthesized in and released from the: a.Anterior pituitary b.Posterior pituitary c.Adrenal medulla d.hypothalamus

10. 9. A 40 year old woman develops an adenoma in the adenohypophysis which secretes excessive amounts of Growth Hormone. Which of the following are to be expected: a.She grows abnormally tall b.Plasma levels of IGF-1 will be high. c.Plasma levels of GHRH will be high d.Bones of the face, hands, and feet will gradually atrophy (get smaller.)

11. 10. Which of the following is released from the adrenal medulla? a.Norepinephrine b.Testosterone c.Adrenocorticotropic hormone d.Cortisol e.Epinepherine

12. 11. Which of the following reaches its target cells by first entering capillaries in the median eminence? a.Norepinephrine b.TSH c.Adrenocorticotropic hormone d.Cortisol e.Dopamine f.Somatostatin g.Corticotropin Releasing Hormone.

13. 12. Which ONE of the following hormones is eliminated most rapidly from the bloodstream? a.Norepinephrine b.TSH c.Cortisol d.T3 e.Estradiol f.Aldosterone

14. 13. What is the source of renin? a.The adrenal cortex b.The adrenal medulla c.The anterior pituitary d.Cell of the macula densa e.Juxtaglomerular cells in the kidney f.The liver

15. 14. Drugs that block the activity of angiotensin converting enzyme are used to treat people with high blood pressure. Blocking ACE will a.Prevent the secretion of renin b.Prevent the formation of Angiotensin I c.Prevent the formation of Angiotensin II d.Cause a person to become very thirsty.

16. 15. Angiotensin II has the following actions: a.Suppresses thirst b.Contracts smooth muscles of blood vessels thereby raising blood pressure c.Stimulates the secretion of aldosterone d.Stimulates the secretion of cortisol

17. 16. In patients with Hashimoto’s disease the thyroid gland is destroyed by cells of the immune system. Which of the following would be elevated in the blood of a person with untreated Hashimoto’s disease ? a.T3 b.T4 c.TSH d.TRH

18. 17. In patients with untreated Hashimoto’s disease which of the following would be expected? a.high blood pressure b.tachycardia (higher than normal heart rate) c.diarrhea d.hypothermia

19. 18. Which of the following hormones cannot be effectively administered in tablets taken orally? a.T3 b.TSH c.Vasopressin d.Cortisol e.Growth hormone

20. 19. Which of the following hormones have receptors on the cell surface of their target cells? a.T3 b.TSH c.TRH d.EPI e.Cortisol f.Aldosterone g.Insulin h.Prolactin

21. 20. Suppose a patient presents with high levels of TSH and high levels of T3 and T4. The diagnosis is most likely a.Primary hyposecretion b.Secondary hyposecretion c.Primary hypersecretion d.Secondary hypersecretion.

22. Answers to Practice Quiz 1 ab 2 abd 3 abd 4 adefg 5 be 6 bdf 7 bce 8 d 9 b 10 ae 11 efg 12 a 13 e 14 c 15 bc 16 cd 17 d 18 bce 19 bcdgh 20 d