1. Avian Influenza Initiatives Canadian Food Inspection Agency Dr. Daniel Schwartz

2. CFIA Avian Influenza Initiatives Reportable Disease Response –Priority Protect animal health, human health, economy. –Dedicated Resources National AI Working Group –Federal: AAFC, CBSA, PHAC, HC, EC –Provincial: MOE, BCMAL, Health Authorities, CDC –Industry, Public –Local Initiatives (BC)

3. CFIA Avian Influenza Initiatives –Multifaceted Prevention –Policy/procedures –Biosecurity –Surveillance Control and Eradication –Destruction –Disposal Recovery –Compensation

4. Prevention Previous Response to AI Only Highly Pathogenic AI –H5 and H7 –Inoculation of chicks causing >75% mortality –Intravenous Pathogenicity Index > 1.2 –Cleavage site analysis of hemagglutinin protein has multiple basic AA.

5. Prevention Current Response to AI Any H5 or H7 AI virus –Low or High Pathogenic strains Any AI A virus causing serious mortality (as per IVPI or ICPI) Resulted from low path strains to high path mutations.

6. Prevention: Biosecurity

7. Prevention Biosecurity –National Office of Biosecurity Capital Region –National Specialty Bird Pilot Projects Assess specific animal husbandry issues –Squab, waterfowl etc. Analyse and Develop effective procedures Implementation Audit/ Verification

8. Prevention Surveillance –Early Detection –Active and Passive –CFIA Serologic survey for H5 and H7 –Compartmental Approach –Primary Breeders, Multipliers, Production Classes

9. Control and Eradication

10. Destruction (Euthanasia)

11. Control and Eradication Humane Destruction –Alternate methods to deal with various species and situations Modified Atmospheric Chambers Gas Mixtures and Delivery –Surge Capacity

12. Control and Eradication Disposal Mass Disposal Options –Infected, Non Infected –Various commodities National Protocols and Procedures Provincial and Site Specific Issues

13. Disposal

16. Recovery Compensation –Review of Health of Animals Act and Regulations –Method of calculating values –Maximum values Vaccination –Vaccines, protocols