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Published byVirginia Morris Modified over 9 years ago
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血管生理
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Hemodynamics w Blood flow: flow velocity is related to total cross-sectional area (sum of total cross sections of all capillaries Laminar flow Turbulent flow
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Blood flow through vessels depends on the pressure gradient and vascular w F=P/R w F:flow rate of blood through a vessel w P: pressure gradient w R: resistance of blood vessels
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Poiseuille’s law
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Arterial system w As a conduit for blood between the heart and capillaries w as a preeusure reservoir for forcing blood into the small-diameter arterioles w dampen oscillations in pressure and flow w control distribution of blood to different capillary network
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Blood pressure w Measurement w direct method w indirect method w systolic pressure w diastolic pressure w pulse pressure
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Direct measurement Transducer BPamplifier Recording system A/D converter PC printer
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Effect of gravity and body position
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Arteriole w The major resistance vessels w control of distribution of blood flow w pressure drop from 97 mmHg to 37 mmHg
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Arteriolar tone w Vasoconstriction ↑ Myogenic activity ↑oxygen ↓carbon dioxide and other metabolites ↑sympathetic stimulation, ADH, AII. Cold w Vasodition ↓ myogenic activity ↓ Oxygen ↑ CO2 and other metabolites ↑adenosine release ↓ sympathetic stimum, histamine release, heat endothelial-derived relaxing factor (EDRF) such as NO
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Venous system w Blood conduit for flowing through w blood reservoir
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Factors influencing venous return w Sleleta-muscle pump w respiratory pump w cardiac pump
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Capillaries and microcirculation
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Lymphatic system
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