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血管生理. Hemodynamics w Blood flow: flow velocity is related to total cross-sectional area (sum of total cross sections of all capillaries Laminar flow Turbulent.

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Presentation on theme: "血管生理. Hemodynamics w Blood flow: flow velocity is related to total cross-sectional area (sum of total cross sections of all capillaries Laminar flow Turbulent."— Presentation transcript:

1 血管生理

2 Hemodynamics w Blood flow: flow velocity is related to total cross-sectional area (sum of total cross sections of all capillaries Laminar flow Turbulent flow

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4 Blood flow through vessels depends on the pressure gradient and vascular w F=P/R w F:flow rate of blood through a vessel w P: pressure gradient w R: resistance of blood vessels

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6 Poiseuille’s law

7 Arterial system w As a conduit for blood between the heart and capillaries w as a preeusure reservoir for forcing blood into the small-diameter arterioles w dampen oscillations in pressure and flow w control distribution of blood to different capillary network

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12 Blood pressure w Measurement w direct method w indirect method w systolic pressure w diastolic pressure w pulse pressure

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14 Direct measurement Transducer BPamplifier Recording system A/D converter PC printer

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17 Effect of gravity and body position

18 Arteriole w The major resistance vessels w control of distribution of blood flow w pressure drop from 97 mmHg to 37 mmHg

19 Arteriolar tone w Vasoconstriction ↑ Myogenic activity ↑oxygen ↓carbon dioxide and other metabolites ↑sympathetic stimulation, ADH, AII. Cold w Vasodition ↓ myogenic activity ↓ Oxygen ↑ CO2 and other metabolites ↑adenosine release ↓ sympathetic stimum, histamine release, heat endothelial-derived relaxing factor (EDRF) such as NO

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22 Venous system w Blood conduit for flowing through w blood reservoir

23 Factors influencing venous return w Sleleta-muscle pump w respiratory pump w cardiac pump

24 Capillaries and microcirculation

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29 Lymphatic system


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