2. Dr. Tony Herdman Michael Smith Scholar Assistant Professor Department of Psychology, SFU Neuroimaging of Reading Supported by: Michael Smith Foundation for Health Research

3. Overview 1)Brain Networks 2)Models of Reading and Language 3)Orthographic Processing 4)Letter-Speech Integration

4. Networks Orthography Phonology Semantics Motor Plan Speech Generation

5. Classical Reading & Language Model Motor Speech Generation Semantics Phonology Orthography

6. Motor Classical Reading & Language Model

7. MEG Brain Reponses ~ 100-300 femtoTesla (10 -15 ) Earths magnetic field ~ 30-60 microTesla (10 -3 )

8. Word Reading CARSOUPSHOEPENBALLKEY

9. Speech (Generation) Sight (orthography) Word Reading RepeatGenerate (Herdman et al., Cerebral Cortex, 2007) MEG

10. Sound (phonology) Speech (Generation) Sight (orthography) Speech Processing RepeatGenerate (Herdman et al., Cerebral Cortex, 2007) MEG

11. Classical Reading & Language Model Motor Speech Generation Semantics Phonology Orthography

13. “To the uneducated, an ‘A’ is just three sticks.” Winnie the Pooh Orthography

14. “To the uneducated, an ‘A’ is just three sticks.” Winnie the Pooh Orthography

15. Model of Reading (Dehaene, et al., TICS, 2005)

16. input A Pseudoletter ? Letter: A KA Z Model of Reading

17. Letter Perception Study Children (12-13 years old) P1 N1 Letter Psuedoletter 7 ms (Herdman et al., submitted) EEG

18. Neural Networks

19. Pesudo letter Letter

20. input A Pseudoletter ? Letter: A KA Z Model of Reading

21. Letter-Sound Pair Learning

23. Phonology Orthography Letter-Sound Pair Learning

24. Motor Speech Generation Semantics Phonology Orthography Reading Impaired Brain

25. (Herdman et al., submitted) Reading Impaired Brain MEG

26. 1)Brain performs complex functions in many different regions 2)Learning modifies brain to make it more efficient 3)Reading impairment can be caused by one or more disruptions in the reading network 4)Findings support a holistic approach to learning and intervention Summary

27. Gene Expression Collaborative for Kids Only GECKO Project Gecko.Project@ubc.ca Experience & Behaviour Neural System Cell & Synapse Gene & Transcription GECKO Project Gene Expression Collaborative for Kids Only Gecko.Project@ubc.ca

28. GECKO Project Gene Expression Collaborative for Kids Only Gecko.Project@ubc.ca

29. Supported by: Michael Smith Foundation for Health Research Thank You for Your Attention

30. Normal Reading Children Rhyming Dyslexic Reading Children Rhyming – Before Intervention Dyslexic Reading Children Increase After Intervention (Temple et al., PNAS, 2003) Fast ForWord Reading Impaired Brain