1. © Cancer Research UK 2011 Registered charity in England and Wales (1089464) and Scotland (SC041666) Colorectal Cancer - UK December 2011 For more information about UK cancer statistics please visit http://info.cancerresearchuk.org/cancerstatshttp://info.cancerresearchuk.org/cancerstats or contact stats.team@cancer.org.ukstats.team@cancer.org.uk

2. © Cancer Research UK 2011 Registered charity in England and Wales (1089464) and Scotland (SC041666) Colorectal Cancer (C18-21), Number of New Cases, Crude and European Age-Standardised (AS) Incidence Rates per 100,000 Population, UK, 2008 *95% LCL and 95% UCL are 95% lower and upper confidence limits around the AS Rate http://info.cancerresearchuk.org/cancerstats/types/bowel/incidence/ EnglandWalesScotland Northern Ireland United Kingdom Male Cases18,0401,3112,14660022,097 Crude Rate71.289.885.868.973.3 ASR57.064.467.765.158.5 ASR - 95% LCL56.260.964.959.957.7 ASR - 95% UCL57.867.970.670.359.3 Female Cases14,6049891,79350817,894 Crude Rate55.964.667.256.257.3 ASR36.939.343.942.537.8 ASR - 95% LCL36.336.941.938.837.3 ASR - 95% UCL37.541.845.946.238.4 Persons Cases32,6442,3003,9391,10839,991 Crude Rate63.476.976.262.465.1 ASR46.150.754.452.847.2 ASR - 95% LCL45.648.652.749.746.8 ASR - 95% UCL46.652.856.155.947.7

3. © Cancer Research UK 2011 Registered charity in England and Wales (1089464) and Scotland (SC041666) Colon Cancer (C18), Number of New Cases, Crude and European Age-Standardised (AS) Incidence Rates per 100,000 Population, UK, 2008 http://info.cancerresearchuk.org/cancerstats/types/bowel/incidence/ EnglandWalesScotland Northern Ireland United Kingdom Male Cases10,9007441,33737813,359 Crude Rate43.051.053.543.444.3 ASR33.935.541.840.834.9 ASR - 95% LCL33.333.039.636.734.3 ASR - 95% UCL34.538.144.145.035.4 Female Cases9,9316311,26236812,192 Crude Rate38.041.247.340.739.0 ASR24.424.230.030.125.0 ASR - 95% LCL23.922.328.327.024.6 ASR - 95% UCL24.926.131.633.225.5 Persons Cases20,8311,3752,59974625,551 Crude Rate40.546.050.342.041.6 ASR28.729.235.234.929.4 ASR - 95% LCL28.327.733.832.429.1 ASR - 95% UCL29.130.836.537.429.8 *95% LCL and 95% UCL are 95% lower and upper confidence limits around the AS Rate

4. © Cancer Research UK 2011 Registered charity in England and Wales (1089464) and Scotland (SC041666) Rectal Cancer (C19-21), Number of New Cases, Crude and European Age-Standardised (AS) Incidence Rates per 100,000 Population, UK, 2008 http://info.cancerresearchuk.org/cancerstats/types/bowel/incidence/ EnglandWalesScotland Northern Ireland United Kingdom Male Cases7,1405678092228,738 Crude Rate28.238.932.425.529.0 ASR23.128.925.924.323.7 ASR - 95% LCL22.526.524.121.123.2 ASR - 95% UCL23.631.327.727.524.2 Female Cases4,6733585311405,702 Crude Rate17.923.419.915.518.2 ASR12.515.113.912.512.8 ASR - 95% LCL12.213.512.710.412.4 ASR - 95% UCL12.916.615.114.513.1 Persons Cases11,8139251,34036214,440 Crude Rate23.030.925.920.423.5 ASR17.421.519.217.917.8 ASR - 95% LCL17.120.118.216.117.5 ASR - 95% UCL17.722.820.219.818.1 *95% LCL and 95% UCL are 95% lower and upper confidence limits around the AS Rate

5. © Cancer Research UK 2011 Registered charity in England and Wales (1089464) and Scotland (SC041666) Colorectal Cancer (C18-21), Average Number of New Cases per Year and Age-Specific Incidence Rates, UK, 2006-2008 http://info.cancerresearchuk.org/cancerstats/types/bowel/incidence/

6. © Cancer Research UK 2011 Registered charity in England and Wales (1089464) and Scotland (SC041666) Colorectal Cancer (C18-21), World Age-Standardised Incidence Rates, World Regions, 2008 Estimates http://info.cancerresearchuk.org/cancerstats/types/bowel/incidence/

7. © Cancer Research UK 2011 Registered charity in England and Wales (1089464) and Scotland (SC041666) Colorectal Cancer (C18-21), European Age-Standardised Incidence Rates, EU-27 Countries, 2008 Estimates http://info.cancerresearchuk.org/cancerstats/types/bowel/incidence/

8. © Cancer Research UK 2011 Registered charity in England and Wales (1089464) and Scotland (SC041666) Colorectal Cancer (C18-21), European Age- Standardised Incidence Rates, Great Britain, 1975-2008 http://info.cancerresearchuk.org/cancerstats/types/bowel/incidence/

9. © Cancer Research UK 2011 Registered charity in England and Wales (1089464) and Scotland (SC041666) Colorectal Cancer (C18-21), European Age- Standardised Incidence Rates, by Age at Diagnosis, Great Britain, 1975-2008 http://info.cancerresearchuk.org/cancerstats/types/bowel/incidence/

10. © Cancer Research UK 2011 Registered charity in England and Wales (1089464) and Scotland (SC041666) Colorectal Cancer (C18-20), One-, Five- and Ten-Year Prevalence, UK, as at 31st December 2006 http://info.cancerresearchuk.org/cancerstats/types/bowel/incidence/ 1 year prevalence 5 year prevalence 10 year prevalence Males14,63551,18378,483 Females11,41540,59465,075 Persons26,05091,777143,558

11. © Cancer Research UK 2011 Registered charity in England and Wales (1089464) and Scotland (SC041666) Colorectal Cancer (C18-21), Number of Deaths, Crude and European Age-Standardised (AS) Mortality Rates per 100,000 Population, UK, 2008 http://info.cancerresearchuk.org/cancerstats/types/bowel/mortality/ *95% LCL and 95% UCL are 95% lower and upper confidence limits around the AS Rate Sex EnglandWalesScotland Northern Ireland United Kingdom Male Deaths7,1784998392428,758 Crude Rate28.434.133. 627.829.1 AS Rate21.823. 626.125.322.3 AS Rate - 95% LCL*21.321.524.322.121.9 AS Rate - 95% UCL*22.325.627.928.522.8 Female Deaths6,1384187461997,501 Crude Rate23.527.328.022.024.0 AS Rate13.614.616.615.114.0 AS Rate - 95% LCL*13.313.215.413.013.7 AS Rate - 95% UCL*14.016.017. 817.214.3 Persons Deaths13,3169171,58544116,259 Crude Rate25.930.630. 724.926.5 AS Rate17.318.620.619.617.7 AS Rate - 95% LCL*17.017.419.617.817.4 AS Rate - 95% UCL*17.619.8721.418.0

12. © Cancer Research UK 2011 Registered charity in England and Wales (1089464) and Scotland (SC041666) Colon Cancer (C18), Number of Deaths, Crude and European Age-Standardised (AS) Mortality Rates per 100,000 Population, UK, 2008 http://info.cancerresearchuk.org/cancerstats/types/bowel/mortality/ Sex EnglandWalesScotland Northern Ireland United Kingdom Male Deaths4,2453315001505,226 Crude Rate16.822.720.017.217.3 AS Rate12.815.415.515.813.2 AS Rate - 95% LCL*12.413.814.113.312.8 AS Rate - 95% UCL*13.117.116.818.313.6 Female Deaths4,0692894401404,938 Crude Rate15.618.916.515.515.8 AS Rate8.910.129.710.29.1 AS Rate - 95% LCL*8.69.08.78.58.8 AS Rate - 95% UCL*9.211.310.611.99.3 Persons Deaths8,31462094029010,164 Crude Rate16.220.718.216.316.6 AS Rate10.612.412.012.710.9 AS Rate - 95% LCL*10.411.511.311.210.7 AS Rate - 95% UCL*10.813.412.814.211.1 *95% LCL and 95% UCL are 95% lower and upper confidence limits around the AS Rate

13. © Cancer Research UK 2011 Registered charity in England and Wales (1089464) and Scotland (SC041666) Rectal Cancer (C19-21), Number of Deaths, Crude and European Age-Standardised (AS) Mortality Rates per 100,000 Population, UK, 2008 http://info.cancerresearchuk.org/cancerstats/types/bowel/mortality/ Sex EnglandWalesScotland Northern Ireland United Kingdom Male Deaths2,933168339923,532 Crude Rate11.611.513. 610.611.7 AS Rate9.08.210.69.59.1 AS Rate - 95% LCL*8.76.99.57.68.8 AS Rate - 95% UCL*9.4 11.811.59.4 Female Deaths2,069129306592,563 Crude Rate7.98.411.56.58.2 AS Rate4.84.57.04.9 AS Rate - 95% LCL*4.53.76.23.64.7 AS Rate - 95% UCL*5.05.37.76.15.1 Persons Deaths5,0022976451516,095 Crude Rate9.79.912.58.59.9 AS Rate6. 76.28.66.96.8 AS Rate - 95% LCL*6.55.57.35. 86.7 AS Rate - 95% UCL*6.9 9.38.07.0 *95% LCL and 95% UCL are 95% lower and upper confidence limits around the AS Rate

14. © Cancer Research UK 2011 Registered charity in England and Wales (1089464) and Scotland (SC041666) Colorectal Cancer (C18-21), Average Number of Deaths per Year and Age-Specific Mortality Rates, UK, 2006-2008 http://info.cancerresearchuk.org/cancerstats/types/bowel/mortality/

15. © Cancer Research UK 2011 Registered charity in England and Wales (1089464) and Scotland (SC041666) Colorectal Cancer (C18-C21), European Age- Standardised Mortality Rates, UK, 1971-2008 http://info.cancerresearchuk.org/cancerstats/types/bowel/mortality/

16. © Cancer Research UK 2011 Registered charity in England and Wales (1089464) and Scotland (SC041666) Colorectal Cancer (C18-21), European Age- Standardised Mortality Rates, by Age at Diagnosis, UK, 1971-2008 http://info.cancerresearchuk.org/cancerstats/types/bowel/mortality/

17. © Cancer Research UK 2011 Registered charity in England and Wales (1089464) and Scotland (SC041666) Colorectal Cancer (C18-21), World Age-Standardised Mortality Rates, World Regions, 2008 Estimates http://info.cancerresearchuk.org/cancerstats/types/bowel/mortality/

18. © Cancer Research UK 2011 Registered charity in England and Wales (1089464) and Scotland (SC041666) Colorectal Cancer (C18-21), European Age-Standardised Mortality Rates, EU-27 Countries, 2008 Estimates http://info.cancerresearchuk.org/cancerstats/types/bowel/mortality/

19. © Cancer Research UK 2011 Registered charity in England and Wales (1089464) and Scotland (SC041666) Colon Cancer (C18) and Rectal Cancer (C19-20, C21.8), One-Year Age-Standardised Relative Survival, England and Wales*, 1971-2008 http://info.cancerresearchuk.org/cancerstats/types/bowel/survival/ Colon Cancer Rectal Cancer * Data is for England only from 1996 onwards

20. © Cancer Research UK 2011 Registered charity in England and Wales (1089464) and Scotland (SC041666) Colon Cancer (C18) and Rectal Cancer (C19-20, C21.8), Five-Year Age-Standardised Relative Survival, England and Wales*, 1971-2008 * Data is for England only from 1996 onwards http://info.cancerresearchuk.org/cancerstats/types/bowel/survival/ Colon Cancer Rectal Cancer

21. © Cancer Research UK 2011 Registered charity in England and Wales (1089464) and Scotland (SC041666) Colon Cancer (C18) and Rectal Cancer (C19-20, C21.8), Ten-Year Age-Standardised** Relative Survival, England and Wales*, 1971-2003 http://info.cancerresearchuk.org/cancerstats/types/bowel/survival/ Colon Cancer Rectal Cancer * Data is for England only from 1996 onwards ** 1971-1985 data not age-standardised

22. © Cancer Research UK 2011 Registered charity in England and Wales (1089464) and Scotland (SC041666) Colorectal Cancer (C18-21), Five-Year Relative Survival by Age at Diagnosis, England, 2004-2008 http://info.cancerresearchuk.org/cancerstats/types/bowel/survival/

23. © Cancer Research UK 2011 Registered charity in England and Wales (1089464) and Scotland (SC041666) Data sources for incidence All charts and tables prepared by Cancer Research UK. Original data sources: 1.Office for National Statistics. Cancer Statistics Registrations, England (Series MB1). http://www.ons.gov.uk/ons/publications/all-releases.html?definition=tcm%3A77-27454 2.Welsh Cancer Intelligence and Surveillance Unit. http://www.wcisu.wales.nhs.uk http://www.wcisu.wales.nhs.uk 3.Information Services Division Scotland. Cancer Information Programme. http:// www.isdscotland.org/cancer http:// www.isdscotland.org/cancer 4.N. Ireland Cancer Registry. http:// www.qub.ac.uk/nicrhttp:// www.qub.ac.uk/nicr 5.Ferlay et al., GLOBOCAN 2008 v1.2, Cancer Incidence and Mortality Worldwide: IARC CancerBase No. 10. Lyon, France: IARC, 2010. http://globocan.iarc.fr/ http://globocan.iarc.fr/

24. © Cancer Research UK 2011 Registered charity in England and Wales (1089464) and Scotland (SC041666) Data sources for prevalence Table prepared by Cancer Research UK. Original data source: 1.National Cancer Intelligence Network (NCIN). One, Five and Ten-Year Cancer Prevalence, June 2010. http://www.ncin.org.uk/publications/reports/default.aspx

25. © Cancer Research UK 2011 Registered charity in England and Wales (1089464) and Scotland (SC041666) Data sources for mortality All charts and tables prepared by Cancer Research UK. Original data sources: 1.Office for National Statistics. Mortality Statistics: Deaths registered in England and Wales (Series DR). http://www.ons.gov.uk/ons/publications/all-releases.html?definition=tcm%3A77-27475 2.General Register Office for Scotland. Vital Events Reference Tables. http://www.gro-scotland.gov.uk/statistics/theme/vital-events/general/ref-tables/ http://www.gro-scotland.gov.uk/statistics/theme/vital-events/general/ref-tables/ 3.Northern Ireland Statistics & Research Agency. Registrar General Annual Reports. http:// www.qub.ac.uk/nicrhttp:// www.qub.ac.uk/nicr 4.Ferlay et al., GLOBOCAN 2008 v1.2, Cancer Incidence and Mortality Worldwide: IARC CancerBase No. 10. Lyon, France: IARC, 2010. http://globocan.iarc.fr/ http://globocan.iarc.fr/

26. © Cancer Research UK 2011 Registered charity in England and Wales (1089464) and Scotland (SC041666) Data sources for survival All charts prepared by Cancer Research UK Original data sources: –1971-1990: Coleman, M.P, et al (1999). Cancer Survival Trends in England and Wales, 1971-1995: Deprivation and NHS Region. Series SMPS No 61. London: The Stationery Office. –1991-1995: ONS. Cancer Survival: England and Wales, 1991-2001, twenty major cancers by age group. –1996-2003: Rachet, B., et al. (2009). 'Population-based cancer survival trends in England and Wales up to 2007', Lancet Oncology, 10, 351-69. Age-standardised relative survival rates were provided by the authors on request. –2004-2008: ONS Statistical Bulletin (2011). Cancer survival in England: Patients diagnosed 2004−2008, followed up to 2009.