1. McGraw-Hill © 2013 by The McGraw-Hill Companies, Inc. All rights reserved. Chapter 13: The Lymphatic System and Body Defense

2. McGraw-Hill © 2013 by The McGraw-Hill Companies, Inc. All rights reserved. 13-2 Learning Outcomes Identify the parts of the lymphatic and immune systems and discuss the function of each part. Recognize the major word parts used in building words that relate to the lymphatic and immune systems. Identify the common diagnoses, laboratory tests, and clinical procedures used in testing and treating disorders of the lymphatic and immune systems. Define the major pathological conditions of the lymphatic and immune systems. Explain the meaning of surgical terms related to the lymphatic and immune systems. Recognize common pharmacological agents used in treating disorders of the lymphatic and immune systems.

3. McGraw-Hill © 2013 by The McGraw-Hill Companies, Inc. All rights reserved. 13-3 Structure and Function Lymphatic / Immune systems share common structures/ functions Immune system uses other systems to maintain function Both contain lymph nodes, spleen, thymus gland, immune cells Lymphatic system site of collection for foreign substances

4. McGraw-Hill © 2013 by The McGraw-Hill Companies, Inc. All rights reserved. 13-4 Lymphatic System Reduces edema Return proteins to blood Traps / filters cellular debris Recycles body fluids Circulates lymphocytes Moves fat from GI tract to blood

5. McGraw-Hill © 2013 by The McGraw-Hill Companies, Inc. All rights reserved. 13-5 Immune System Body defense against foreign bodies Fights infections Produces antibidies immunoglobulins

6. McGraw-Hill © 2013 by The McGraw-Hill Companies, Inc. All rights reserved. 13-6 Location lymph nodes

7. McGraw-Hill © 2013 by The McGraw-Hill Companies, Inc. All rights reserved. 13-7 Lymph Circulation

8. McGraw-Hill © 2013 by The McGraw-Hill Companies, Inc. All rights reserved. 13-8 Lymphatic Vessels

9. McGraw-Hill © 2013 by The McGraw-Hill Companies, Inc. All rights reserved. 13-9 Lymph node

10. McGraw-Hill © 2013 by The McGraw-Hill Companies, Inc. All rights reserved. 13-10 Spleen / Thymus

11. McGraw-Hill © 2013 by The McGraw-Hill Companies, Inc. All rights reserved. 13-11 Lymphatic Organs Involves network of vessels Plasma can enter cellar body Interstitial fluid Provides nutrients during fluid exchange Drainage system to remove fluid Concentrates foreign bodies

12. McGraw-Hill © 2013 by The McGraw-Hill Companies, Inc. All rights reserved. 13-12 Lymphatic System lymph lymphatic pathways lymphatic vessels lymph node spleen thymus gland T- cells (T lymphocytes) B lymphocytes, B- cells thymosin

13. McGraw-Hill © 2013 by The McGraw-Hill Companies, Inc. All rights reserved. 13-13 Node and Vessels

14. McGraw-Hill © 2013 by The McGraw-Hill Companies, Inc. All rights reserved. 13-14 Combining Terms aden(o)gland immun(o)immunity lymph(o)lymph lymphaden(o)lymph nodes lymphangi(o)lymphatic vessels spleen(o)spleen thym(o)thymus tox(o), toxi, poison toxico

15. McGraw-Hill © 2013 by The McGraw-Hill Companies, Inc. All rights reserved. 13-15 The Immune System Reticuloendothelial system Hematopoietic system Phagocytic system Lymphoid system

16. McGraw-Hill © 2013 by The McGraw-Hill Companies, Inc. All rights reserved. 13-16 Hematopoietic System Production of blood cells Erythrocytes (RBC) Leukocytes (WBC) Thrombocytes (platelets)

17. McGraw-Hill © 2013 by The McGraw-Hill Companies, Inc. All rights reserved. 13-17 Phagocytic System Immune / bodies defense Lymph nodes, spleen, thymus gland Protects the body Skin and tonsils role in defense

18. McGraw-Hill © 2013 by The McGraw-Hill Companies, Inc. All rights reserved. 13-18 Diagnostic, Procedural, Labs Assist in diagnosing medical conditions Used in combinations Lead to final diagnosis Assist in treatment planning

19. McGraw-Hill © 2013 by The McGraw-Hill Companies, Inc. All rights reserved. 13-19 Radiograph Lymphatic Vessels

20. McGraw-Hill © 2013 by The McGraw-Hill Companies, Inc. All rights reserved. 13-20 Lymphocyte Micrograph

21. McGraw-Hill © 2013 by The McGraw-Hill Companies, Inc. All rights reserved. 13-21 Diagnostics Review enzyme-linked immunosorbent assay EIA, ELISA western blot

22. McGraw-Hill © 2013 by The McGraw-Hill Companies, Inc. All rights reserved. 13-22 Pathological Terms Diseases attack lymph tissue, spread by lymphatic pathways, flourish when immunity suppressed, over reacting to invader, attack the body itself

23. McGraw-Hill © 2013 by The McGraw-Hill Companies, Inc. All rights reserved. 13-23 HIV Virus

24. McGraw-Hill © 2013 by The McGraw-Hill Companies, Inc. All rights reserved. 13-24 T- / B- cell activation

25. McGraw-Hill © 2013 by The McGraw-Hill Companies, Inc. All rights reserved. 13-25 Kaposi Sarcoma

26. McGraw-Hill © 2013 by The McGraw-Hill Companies, Inc. All rights reserved. 13-26 Opportunistic Process Infection TypeArea Candidiasiscaused by fungus, Candida albicans GI, Respiratory Skin, reproductive Cytomegaloviruscaused by fungus, Candida albicans Infect cells or organs, eyes, cause swelling

27. McGraw-Hill © 2013 by The McGraw-Hill Companies, Inc. All rights reserved. 13-27 Opportunistic Process Kaposi’s sarcoma malignancy arising from capillary linings skin and lymph nodes (MAI) MAIcaused by bacterium found in soil and water systemic infection with fever diarrhea, lung and blood disease and wasting

28. McGraw-Hill © 2013 by The McGraw-Hill Companies, Inc. All rights reserved. 13-28 Opportunistic Process Pneumocystis carinii pneumonia (PCP) caused by parasite lungs—a particularly dangerous type of pneumonia

29. McGraw-Hill © 2013 by The McGraw-Hill Companies, Inc. All rights reserved. 13-29 How HIV is transmitted Sexual contact Contaminated needles During birth Blood transfusion

30. McGraw-Hill © 2013 by The McGraw-Hill Companies, Inc. All rights reserved. 13-30 How HIV is not transmitted Casual contact Objects: toilet seats, deodorant, doorknobs, mosquitoes Sneezing / coughing Sharing food Swimming with infected person

31. McGraw-Hill © 2013 by The McGraw-Hill Companies, Inc. All rights reserved. 13-31 Allergic Response Allergies are a disorder of the immune system that affect millions of people every year.

32. McGraw-Hill © 2013 by The McGraw-Hill Companies, Inc. All rights reserved. 13-32 Common Allergies

33. McGraw-Hill © 2013 by The McGraw-Hill Companies, Inc. All rights reserved. 13-33 Immediate-reaction Allergy

34. McGraw-Hill © 2013 by The McGraw-Hill Companies, Inc. All rights reserved. 13-34 Pharmacological Terms Chemotherapy / Radiation Managed for symptoms AIDS / “cocktails” Antiviral drugs = block growth Antimicroorganism agent = pentamidine prevents PC

35. McGraw-Hill © 2013 by The McGraw-Hill Companies, Inc. All rights reserved. 13-35 Chapter Review Identify the parts of the lymphatic and immune systems and discuss the function of each part. Recognize the major word parts used in building words that relate to the lymphatic and immune systems. Identify the common diagnoses, laboratory tests, and clinical procedures used in testing and treating disorders of the lymphatic and immune systems. Define the major pathological conditions of the lymphatic and immune systems. Explain the meaning of surgical terms related to the lymphatic and immune systems. Recognize common pharmacological agents used in treating disorders of the lymphatic and immune systems.