1. Current concepts: tissue engineering and regenerative medicine applications in the ankle joint by S. I. Correia, H. Pereira, J. Silva-Correia, C. N. Van Dijk, J. Espregueira-Mendes, J. M. Oliveira, and R. L. Reis Interface Volume 11(92):20130784 March 6, 2014 ©2014 by The Royal Society

2. TERM applications on the ankle joint. S. I. Correia et al. J. R. Soc. Interface 2014;11:20130784 ©2014 by The Royal Society

3. (a) Grade 3 ulcer, (b) PRP application in wound and (c) chronic infected wound protected by collagen membrane with gentamicin sulfate. S. I. Correia et al. J. R. Soc. Interface 2014;11:20130784 ©2014 by The Royal Society

4. (a) Achilles tendon defect partial rupture identified in T2 MRI (arrow) and (b) endoscopic view of the defect. S. I. Correia et al. J. R. Soc. Interface 2014;11:20130784 ©2014 by The Royal Society

5. Photograph of the gellan gum microparticles obtained by precipitation in a phosphate buffered saline (pH 7.4) solution and possessing a size between 500 and 2000 µm. S. I. Correia et al. J. R. Soc. Interface 2014;11:20130784 ©2014 by The Royal Society

6. (a) Scanning electron microscopy image of MSCs seeded onto SPCL scaffolds and maintained in a standard osteogenic culture medium, after 14 days of culturing. S. I. Correia et al. J. R. Soc. Interface 2014;11:20130784 ©2014 by The Royal Society

7. Photographs of gellan gum hydrogels: (a) single and (b) bilayered. S. I. Correia et al. J. R. Soc. Interface 2014;11:20130784 ©2014 by The Royal Society

8. (a) Photograph of TruFit PLGA-based scaffold delivery device, (b) defect zone prepared to receive the plug and (c) arthroscopically implanted device to resurface the defect preserving joint congruency. S. I. Correia et al. J. R. Soc. Interface 2014;11:20130784 ©2014 by The Royal Society

9. (a) Per-operative photograph of Hemicap ankle implant after tibial osteotomy and control X-ray in (b) frontal and (c) lateral views at 1 year follow-up. S. I. Correia et al. J. R. Soc. Interface 2014;11:20130784 ©2014 by The Royal Society