1. Orange Team Ryan Null Project Manager CS 411 Orange Team 04 May, 2009 1 Old Dominion University: Computer Science CS 411 Orange Team - HEART

2. Team Orange Professor Brunelle David Algorithm and Integration Developer Ryan Simulation Interface developer Andrew Sensor Integration Developer Spencer GUI and Database Developer Nicole GUI and Database Developer Experts Dr. Daniel Garland M.D. President of Pathologist Department Obici Hospital Suffolk Mrs. Janet Jackson BSN RN HCMSDM Regulatory Compliance Manager Amerigroup Corporation Virginia Beach 04 May, 20092 Old Dominion University: Computer Science CS 411 Orange Team - HEART

3. Cardiac Rehabilitation Retention Cardiac patients do not commit to the long-term rehabilitation necessary to extend their life. 04 May, 20093 Old Dominion University: Computer Science CS 411 Orange Team - HEART

4. Societal Cost of Cardiac Failure The direct and indirect cost to the U. S. in 2008 alone are staggering. [1] $156 billion for Cardiac Heart Disease $448 billion for Cardio Vascular Disease [1] http://www.americanheart.org/presenter.jhtml?identifier=3050603 04 May, 20094 Old Dominion University: Computer Science CS 411 Orange Team - HEART

5. Need for Cardiac Rehabilitation Is Increasing 22 million people experience heart failure every year [1] 5 million people in the United States are living with a heart condition [2] 500, 000 additional cases are diagnosed each year [1] Popular Science Magazine, December 2008, 61 - 63 [2] http://www.americanheart.org/presenter.jhtml?identifier=3047844 04 May, 20095 Old Dominion University: Computer Science CS 411 Orange Team - HEART

6. 80% of Patients Cease Cardiac Rehabilitation Team Orange SBIR page 9 04 May, 20096 Old Dominion University: Computer Science CS 411 Orange Team - HEART

7. Rehabilitation Exercises Extend Life Doctor prescribed exercises are essential to successful rehabilitation. [1] Increased heart strength and mobility Lower blood pressure, cholesterol, and BMI Reduced emotional stress, depression, and anxiety [1] http://www.mayoclinic.com/health/cardiac-rehabilitation/HB00017 04 May, 20097 Old Dominion University: Computer Science CS 411 Orange Team - HEART

8. Challenges to Monitoring Cardiac Patient Exercise Team Orange SBIR Appendix J 04 May, 20098 Old Dominion University: Computer Science CS 411 Orange Team - HEART

9. Tools to Encourage Rehabilitation Are Needed According to Dr. Suaya M.D., Ph.D., and lead author of a study in Circulation: Journal of the American Heart Association. “We need to find ways to increase the use of cardiac rehabilitation, because it is used very little by patients who could benefit a lot…” [1] The A.H.A. “recommends physicians aggressively encourage cardiac rehabilitation…” [1] http://www.americanheart.org/presenter.jhtml?identifier=3050603 04 May, 20099 Old Dominion University: Computer Science CS 411 Orange Team - HEART

10. Patient Involvement Is Key to Rehabilitation A rehabilitation study at Beaumont Hospitals concluded: “Active involvement of the patient and family is vital to the success of the program.” [1] And ABC reports “[…] If the patient is actively engaged […] they feel like they have some control over what they will do and how they will do it.” [2] [1] https://www.beaumonthospitals.com/health-library/P06321 [2] http://www.abc.net.au/rn/healthreport/stories/2007/2023663.htm 04 May, 200910 Old Dominion University: Computer Science CS 411 Orange Team - HEART

11. Current Rehabilitation System Team Orange SBIR page 11 04 May, 200911 Old Dominion University: Computer Science CS 411 Orange Team - HEART

12. Goals of Cardiac Rehabilitation Retention Solutions Lifestyle Education Increase involvement in rehabilitation process Illustrate concrete benefits of changes through historical data Support Accountability and control of exercise regimen Positive feedback on progress Team Orange SBIR page 9-10 04 May, 200912 Old Dominion University: Computer Science CS 411 Orange Team - HEART

13. H eart E xercise A ccelerometer R ehabilitation T ool Contains mechanics to monitor and record patients’ heart rate, exercise type, repetitions, and duration each time they exercise Give feedback to reinforce positive progress with reports on exercises performed and heart strength Be utilized during rehabilitation, home exercises, and patient follow-ups Be non-intrusive and not substantially modify established rehabilitation processes 04 May, 200913 Old Dominion University: Computer Science CS 411 Orange Team - HEART

14. Modified Rehabilitation System Team Orange SBIR page 12 04 May, 200914 Old Dominion University: Computer Science CS 411 Orange Team - HEART

15. H.E.A.R.T. Technical Overview Team Orange SBIR page 13 04 May, 200915 Old Dominion University: Computer Science CS 411 Orange Team - HEART

16. H.E.A.R.T. Cardiac Patient Use Team Orange SBIR page 14 04 May, 200916 Old Dominion University: Computer Science CS 411 Orange Team - HEART

17. Patient and Rehabilitation Software Team Orange H.E.A.R.T. Prototype User’s Manual 04 May, 200917 Old Dominion University: Computer Science CS 411 Orange Team - HEART

18. Cardiac Patient Software Report Team Orange H.E.A.R.T. Prototype User’s Manual 04 May, 200918 Old Dominion University: Computer Science CS 411 Orange Team - HEART

19. Required Measurements for Cardiac Rehabilitation Tools Team Orange SBIR Appendix J 04 May, 200919 Old Dominion University: Computer Science CS 411 Orange Team - HEART

20. H.E.A.R.T. Capabilities Team Orange SBIR page 16 04 May, 200920 Old Dominion University: Computer Science CS 411 Orange Team - HEART

21. Target Market: Rehabilitation Team Orange SBIR Appendix B 04 May, 200921 Old Dominion University: Computer Science CS 411 Orange Team - HEART

22. H.E.A.R.T. Risk Analysis Probability Not LikelyLowModerateHighExpected Impact ExtremeT1, F1 HighF2C1 ModerateT3C2T2F3 Low Negligible ItemTechnical RisksProbabilityImpact T1Hardware and Software Interoperability25 T2Hardware and Software Accuracy13 T3Malfunction (Device and Software)33 ItemFinancial RisksProbabilityImpact F1FDA Rejection25 F2Insurance Rejection24 F3Market Competition43 ItemCustomer RisksProbabilityImpact C1Rehabilitation Rejection34 C2Proper Utilization23 04 May, 200922 Old Dominion University: Computer Science CS 411 Orange Team - HEART

23. Budget Overview PhaseStaffingHardwarePhase Total Phase 1 (6 months)‏$23,835$1,599$99,800 Phase 2 (Two Years)‏$567,034$137,397$704,430 Phase 3 (Per Year)‏$362,028$266,044$628,072 Total Phases 1-3$952,897$405,040$1,357,937 Team Orange SBIR page 29 - 31 04 May, 200923 Old Dominion University: Computer Science CS 411 Orange Team - HEART

24. H.E.A.R.T. Prototype Constraints 04 May, 200924 Old Dominion University: Computer Science CS 411 Orange Team - HEART ConditionTypeEffect on Requirements Cost prevents integration of a programmable unit and hard-wired sensors. Constraint Simulation Interface uses third-party and proprietary software to integrate. Cannot demonstrate synchronization without hard-wired sensors. Constraint Synchronization between GUIs and prototype will be simulated. Prototype GUI’s are not fully developed. Constraint Installation of GUI will not be demonstrated. Algorithms discriminate unknown exercises Assumption A representative set of exercises has been selected. Patient will use proper form for exercises. AssumptionDiscrimination complexity reduced by consistent data.

25. H.E.A.R.T. Prototype 04 May, 200925 Old Dominion University: Computer Science CS 411 Orange Team - HEART

26. H.E.A.R.T. Prototype Demo 04 May, 200926 Old Dominion University: Computer Science CS 411 Orange Team - HEART Please refer to the H.E.A.R.T. Prototype Demonstration Scenarios Handout

27. H.E.A.R.T. Risk Mitigation 04 May, 200927 Old Dominion University: Computer Science CS 411 Orange Team - HEART Probability Not LikelyLowModerateHighExpected Extreme T1 High C1 ImpactModerateT3C2T2 Low Negligible ItemTechnical RisksProbabilityImpact T1Hardware and Software Interoperability15 T2Hardware and Software Accuracy23 T3Malfunction (Device and Software)13 ItemCustomer RisksProbabilityImpact C1Rehabilitation Rejection24 C2Proper Utilization13

28. H.E.A.R.T. Conclusion Financial Incentives Generate historical data on exercises and their associated heart rate for scientific study and innovation Reduce health care costs by decreasing future cardiac intervention and hospitalization 04 May, 200928 Old Dominion University: Computer Science CS 411 Orange Team - HEART

29. H.E.A.R.T. Conclusion Cardiac Rehabilitation Patient Incentives The patient will Be involved in managing their rehabilitation through feedback on progress Develop and maintain positive long-term lifestyle changes as recommended by their rehabilitation specialists Be educated and accountable for their long term exercise and rehabilitation regimen 04 May, 200929 Old Dominion University: Computer Science CS 411 Orange Team - HEART