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Intercellular Adhesion Molecule-1 (ICAM-1, CD54) Is Increased in Adhesive Capsulitis by Yang-Soo Kim, Jung-Man Kim, Yun-Gyoung Lee, Oak-Kee Hong, Hyuk-Sang.

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Presentation on theme: "Intercellular Adhesion Molecule-1 (ICAM-1, CD54) Is Increased in Adhesive Capsulitis by Yang-Soo Kim, Jung-Man Kim, Yun-Gyoung Lee, Oak-Kee Hong, Hyuk-Sang."— Presentation transcript:

1 Intercellular Adhesion Molecule-1 (ICAM-1, CD54) Is Increased in Adhesive Capsulitis by Yang-Soo Kim, Jung-Man Kim, Yun-Gyoung Lee, Oak-Kee Hong, Hyuk-Sang Kwon, and Jong-Hoon Ji J Bone Joint Surg Am Volume 95(4):e18 February 20, 2013 ©2013 by The Journal of Bone and Joint Surgery, Inc.

2 Fig. 1-A Each bright square dot on the membrane corresponds to detection of a specific gene. Yang-Soo Kim et al. J Bone Joint Surg Am 2013;95:e18 ©2013 by The Journal of Bone and Joint Surgery, Inc.

3 The concentration of ICAM-1 (intercellular adhesion molecule-1) messenger RNA (mRNA) was determined in capsular tissue from the patients with adhesive capsulitis (n = 13) and the control patients (n = 6) with use of quantitative real-time PCR (polymerase ch... Yang-Soo Kim et al. J Bone Joint Surg Am 2013;95:e18 ©2013 by The Journal of Bone and Joint Surgery, Inc.

4 Figs. 3-A through 3-H Immunohistochemical results. Yang-Soo Kim et al. J Bone Joint Surg Am 2013;95:e18 ©2013 by The Journal of Bone and Joint Surgery, Inc.

5 Figs. 4-A and 4-B The western blotting results clearly show that the concentration of ICAM-1 (intercellular adhesion molecule-1) molecules in the glenohumeral synovial fluid was greater in the patients with adhesive capsulitis compared with the control pati... Yang-Soo Kim et al. J Bone Joint Surg Am 2013;95:e18 ©2013 by The Journal of Bone and Joint Surgery, Inc.

6 The total soluble ICAM-1 (intercellular adhesion molecule-1) level was quantified by enzyme- linked immunosorbent assay (ELISA) in serum from normal controls (n = 14), patients with adhesive capsulitis (n = 32), and patients with diabetes mellitus (n = 20). Yang-Soo Kim et al. J Bone Joint Surg Am 2013;95:e18 ©2013 by The Journal of Bone and Joint Surgery, Inc.

7 The genes for fibrosis-related cytokines and growth factors were evaluated in cultured normal human synovial cells after one and three days of treatment with ICAM-1 (intercellular adhesion molecule-1) with and without glucose. Yang-Soo Kim et al. J Bone Joint Surg Am 2013;95:e18 ©2013 by The Journal of Bone and Joint Surgery, Inc.


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