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2. 2 Micro-ingredient Premixing Sajjad Hussain 2006-ag-1006 AN-621

3. 3 Premixing A premix is a mixture of vitamins, trace minerals, medicaments, feed supplements and diluents

4. 4 Objectives To deliver the micro ingredients in a manner desired by the consumer Mixing ingredients together to result in a homogeneous blend has remained unchanged Value added solution for feed with sustainable safety and quality

5. 5 Premix industry is charged with responsibility of manufacturing a high quality premix consistently, efficiently and economically

6. 6 Quality Management In Premixing Production Improve and sustain the quality premix Three interrelated elements are (quality design, quality control and quality improvement)

7. 7 Quality Management In Premixing Production

8. 8 Flow Chart Of Premix Production Process

9. 9 Premix Manufacturing Process Comprises A. Raw materials 1.Selection and specification 2.Purchase 3.Receipt and storage 4.Sampling and analysis 5.Processing

10. 10 B. Formulation C. Weighing D. mixing E. Packaging F. Labeling G.Storage of finished premix

11. 11 A. Raw materials 1.Selection and specification Amongst vitamins stability forms Bioavailability, potency and reactivity of trace minerals Specification should be mention by AAFCO,AOAC,AFMA,I.P

12. 12 2. Purchase Of Raw Materials Procured from approved venders Not receive without certificate of analysis

13. 13 Nutrients And Its Sources

14. 14 3.Receipt And Storage Of Raw Materials Receiver should have much information Sacked ingredients should check for identification Complete detail on stock records Prevent development of stacking resistance (not more than 10 bags to be stored)

15. 15 4. Sampling and Analysis Followed by quality assurance programme Sample should be done from bottom, center and top layer of bag Mix and analyze materials (Instruments like H.P.L.C,flame photometer and spectrophotometer)

16. 16 5.Processing Processing include i. Sieving ii. Milling

17. 17 B.Formulation Critical in manufacturing premix Physical,chemical characters and bioavailability of ingredients

18. 18 The Batch Sheet Should Comprise Following Details Name of the premix Code of premix Production date Batch no. of premix Batch size List of ingredients to be mixed Batch no. of ingredients to be mixed Mixing order of ingredients Actual quantity of ingredients to be taken Mixer name and mixing time Instructions regarding packing and mixing Provision for signatures

19. 19 C. WEIGHING Difficult to achieving desire nutrients without weighing Precision in weighing is critical for (Selenium, where mistakes may even prove toxic ) Assurance in weighing can be achieved by calibrating balances

20. 20 D. MIXING Heart of any premix-manufacturing unit In order to obtain a homogenous blend( A. Micro mixing and B. Macro mixing) Content uniformity of the premix is based on i. Type of Mixer ii. Mixing Time iii.Mixing order

21. 21 E. Packaging Provides barrier against light, moisture, oxygen No chemical interactions with the premix Provides good printing surface Sturdy enough to withstand the transport pressure

22. 22 F. Labeling Labeling of premix serves two purposes 1. Provides complete information about the premix 2. Gives an identity to the premix and helps in differentiating from other premixes

23. 23 A premix label should have following information  Name of the premix  Composition  Dosage of premix  Net weight of premix contained in the package (in kg)  Batch number  Storage conditions  Name and address of the manufacturer with logo  Disclaimer note if any

24. 24 G. STORAGE Following steps are recommended The temperature and humidity of warehouse Keep the area clean Keep the area free from pests and rodents Design the storage areas to facilitate the FIFO (First in First Out) policy No bag should be stored without any label