1. University of Iowa Cancer Prevention and Control Research Network Sue Curry, Ph.D., Principal Investigator This presentation was supported by Cooperative Agreement Number 1U48DP005021-01REV from the Centers for Disease Control and Prevention. The findings and conclusions in this presentation are those of the author(s) and do not necessarily represent the official position of the Centers for Disease Control and Prevention.

2. AIMS Accelerate implementation of E-B CPC strategies Reduce cancer risk Improve participation in e-b strategies Enhance efforts to reach underserved populations –Multi-level engagement with individuals, community organizations & health systems

3. Resources Outstanding faculty with broad expertise and experience Institutional support & infrastructure Surveillance Robust and varied community partnerships

4. Faculty NameExpertise Sue CurryHealth behavior & health services research Edith ParkerCBPR, program evaluation, translation and dissemination research Barbara BaqueroCBPR with Latino populations Faryle NothwehrEvaluation & dissemination research, rural community collaborations for healthy eating Jason Daniel-UlloaHealth disparities, qualitative research in ethnic minority populations Elizabeth ChrischillesCancer prevention/population sciences leadership; core population data resources, multi-center trials Barcey LevyIowa Research Network, colorectal cancer screening Natoshia AskelsonHealth communications, colorectal cancer screening, HPV vaccination Brad McDowellPopulation data resources, Iowa Cancer Consortium (co-chair of Data & Evaluation Committee; development of Iowa Cancer Plan) Tina DeveryExecutive director of Iowa Cancer Consortium Chuck LynchCancer surveillance, cancer epidemiology, environmental epidemiology; PI and Medical Director of Iowa’s SEER registry

5. Institutional Support/Infrastructure Collaborative culture across UI colleges Institute for Clinical & Translational Research Holden Comprehensive Cancer Center CPH Communications & External Relations Institute for Public Health Practice Iowa Institute for Public Health Research & Policy Center for Public Health Statistics Business Leadership Network

6. Surveillance Data State Health Registry of Iowa –NCI SEER Registry Cohort Studies –Agricultural Health Study Data linkages –SEER-Medicare, SEER-MHOS, Medicare, Medicaid Data, SEER-Breast & Cervical Cancer Screening Program, SEER-Colorectal Cancer Screening Program Iowa Health Fact Book

7. Community Partnerships Iowa Cancer Consortium Iowa Primary Care Association (14 FQHC’s) Iowa Department of Public Health Local Health Departments UI Health Alliance Iowa Hospital Association Iowa Research Network (IRENE) Partnerships in racial/ethnic diverse communities Advisory boards –PRC-RH Advisory Boards (local and state) –CPH Board of Advisors

8. Strategies for Studying Dissemination Identify grand challenges –Surveillance Identify evidence-based approaches for intervention – USPSTF, CPSTF Apply state of the art research methods to evaluate dissemination strategies Determine metrics and timeline for assessing dissemination

9. Pilot Project – HPV Vaccination Surveillance –HP2020 goal = 80%; Iowa = 36% (lower among African Americans) Evidence-based interventions –CDC Advisory Committee on Immunization Practices (ACIP) recommendations –CPSTF strategies to Enhance access to vaccination services (4) Increase community demand (4) Provider/system interventions (5)

10. Pilot Project – HPV Vaccination Faculty and collaborations –Drs. Askelson & Daniel-Ulloa have ongoing work –Existing collaborations with 5 counties in Iowa with highest African American population –Priority of Iowa Cancer Consortium –Partnerships with FQHC’s through Iowa Primary Care Association –Partnerships with state & local health departments

11. Pilot Project – HPV Vaccination Research design idea –Multiple baseline study to evaluate demand and system interventions – alone & in combination Designed in collaboration with local community partners –4 groups of 5 communities (e.g., 2 per network member) –Outcomes include vaccination rates, key informant data from health systems, organizational interviews in adjacent communities

12. Multiple Baseline Design Community Groups (n=20) Time Periods & Intervention Activities T1 -6 month observationfor baseline assessment Intervention T2-6 month follow-up Intervention T3-12 month follow-up Intervention T4-18 month follow-up Group 1xNonex xCombinedX Group 2XDemandX +System (combined) XCombinedX Group 3XSystemX +Demand (combined) XCombinedX Group 4XCombinedX X X

13. Dummy Data….

14. Questions, comments?