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Published byEthan Kirk
Modified over 6 years ago
Proton Pump InhibitorsAppropriate Use in General Practice
Life before PPIs The history of dyspepsia Surgery and dietVagotomy/Pyloroplasty Steamed fish and milk puddings H2-receptor antagonists Tagamet & SKF Zantac & Glaxo
Proton Pump InhibitorsLosec (Omeprazole)(Astra) Zoton (Lansoprazole)(Wyeth) Pariet (Rabeprazole)(Janssen) Nexium (Esomeprazole)(Astra)
NICE Guidance Issued in 2000Targeted use to make best use of resources
Dyspeptic Symptoms Diagnosed or not? Non-ulcer DyspepsiaPeptic Ulceration GORD
Peptic Ulceration Helicobacter-related? NSAID-related? ERADICATECo-Prescribe PPI if cannot stop NSAID
Gastro-Oesophageal RefluxSevere healing dose PPI until symptoms controlled maintenance dose to prevent recurrence Complicated stricture, ulcer, haemorrhage etc full dose maintained Mild alternative Rx: antacid, alginate, H2RA
Non-ulcer Dyspepsia Use Acid Suppressor (H2RA) NOT PPIStep-up or Step-down
Investigation Over 55 ENDOSCOPY Alarm Symptoms ENDOSCOPYdysphagia anaemia progressive weight loss Under 45 NO INVESTIGATION DEBATABLE
Nursing Care of Patients WithUpper GI Disturbances
Drugs Affecting the Gastrointestinal System
Antacids L. Scheffler 1.
Dyspepsia, Peptic Ulcer Disease and Helicobacter Pylori
Anti-Ulcer Agents Michael Alwan November 11, 2004
Drugs Used For Peptic Ulcer
What is dyspepsia? A non-specific group of symptoms that relate to the upper GI tract: Epigastric pain Feelings of bloating or fullness Heartburn Rome.
Topics Background Treatment Reading Assignments/Questions References
GORD & Peptic ulcers Dr Alex Timperley FY2. Objectives Aetiology Signs & symptoms Investigations Management Complications Example cases.
Drugs Used in Gastrointestinal System Prof. : Abdulqader A. ALHAIDER.
DYSPEPSIA Dr.Vishal Rathore. Dyspepsia popularly known as indigestion meaning hard or difficult digestion, is a medical condition characterized by chronic.
Copyright (c) 2004 Elsevier Inc. All rights reserved. Drugs for Peptic Ulcer Disease Chapter 73.
GERD and Peptic ulcer disease
Gastroenterology in General Practice. Gastroenterology Dyspepsia Ulcer disease Non-ulcer dyspepsia Helicobacter pylori Altered Bowel Habit Constipation.
Norman Evans Chief Pharmacist Wandsworth PCT South West London Finding The Resources – The Cost Challenge.
BSG Guidelines Management of Dyspepsia
HEALING ULCERS Liquorice extract (licorice) for > 2000 years in China.... helps ulcers heal Prostaglandins are natural hormones that help heal holes in.
D YSPEPSIA & P EPTIC U LCER By Dr. Zahoor 1. D YSPEPSIA What is Dyspepsia ? Dyspepsia is used to describe number of upper abdominal symptoms such as.
DYSPEPSIA Leena Patel 1/2/12. OVERVIEW Statistics Red flags Management H-pylori testing and treatment.
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