2. TO PEE OR NOT TO PEE A STUDY OF URINATION

3. Urinary system Major organ is the kidney Also includes the ureters, the urinary bladder and the urethra

4. Functions of the Urinary System Slide 15.1a Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Elimination of waste products  Nitrogenous wastes  Toxins  Drugs

5. Functions of the Urinary System Slide 15.1b Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Regulate aspects of homeostasis  Water balance  Electrolytes  Acid-base balance in the blood  Blood pressure  Red blood cell production  Activation of vitamin D

6. Kidney Filters wastes out of blood (180 L per day) Unit of function is the nephron

7. Regions of the Kidney Slide 15.5 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Renal cortex – outer region  Renal medulla – inside the cortex  Renal pelvis – inner collecting tube Figure 15.2b

8. Types of Nephrons Slide 15.11a Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Cortical nephrons  Located entirely in the cortex  Includes most nephrons Figure 15.3a

9. Types of Nephrons Slide 15.11b Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Juxtamedullary nephrons  Found at the boundary of the cortex and medulla Figure 15.3a

10. Filters blood by taking everything (except blood cells) out and putting back what is needed (reabsorption) Nephron

11. Glomerulus Slide 15.9a Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  A specialized capillary bed  Attached to arterioles on both sides (maintains high pressure)  Large afferent arteriole  Narrow efferent arteriole Figure 15.3c

12. Renal Tubule Slide 15.10 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Glomerular (Bowman’s) capsule  Proximal convoluted tubule  Loop of Henle  Distal convoluted tubule Figure 15.3b

13. Urine Formation Processes Slide 15.13 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Filtration  Reabsorption  Secretion Figure 15.4

14. Materials Not Reabsorbed Slide 15.16 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Nitrogenous waste products  Urea  Uric acid  Creatinine  Excess water

15. Secretion – Reabsorption in Reverse Slide 15.17 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Some materials move from the peritubular capillaries into the renal tubules  Hydrogen and potassium ions  Creatinine  Materials left in the renal tubule move toward the ureter

16. Formation of Urine Slide 15.18 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Figure 15.5

17. Urinary Bladder Slide 15.21a Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Smooth, collapsible, muscular sac  Temporarily stores urine Figure 15.6

18. URINARY BLADDER Holds about 600 mL Pain at 400 mL Elastic and when it is stretched, sends message to brain to go Urine flows out the urethra

19. Urethra Gender Differences Slide 15.24a Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Length  Females – 3–4 cm (1 inch)  Males – 20 cm (8 inches)  Location  Females – along wall of the vagina  Males – through the prostate and penis

20. Micturition (Voiding) Slide 15.25 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Both sphincter muscles must open to allow voiding  The internal urethral sphincter is relaxed after stretching of the bladder  Activation is from an impulse sent to the spinal cord and then back via the pelvic splanchic nerves  The external urethral sphincter must be voluntarily relaxed

21. Maintaining Water Balance Slide 15.26 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Normal amount of water in the human body  Young adult females – 50%  Young adult males – 60%  Babies – 75%  Old age – 45%  Water is necessary for many body functions and levels must be maintained

22. Distribution of Body Fluid Slide 15.27 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Intracellular fluid (inside cells)  Extracellular fluid (outside cells)  Interstitial fluid  Blood plasma Figure 15.7

23. Maintaining Water Balance Slide 15.29 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Water intake must equal water output  Sources for water intake  Ingested foods and fluids  Water produced from metabolic processes  Sources for water output  Vaporization out of the lungs  Lost in perspiration  Leaves the body in the feces  Urine production

24. Maintaining Water Balance Slide 15.30 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Dilute urine is produced if water intake is excessive  Less urine (concentrated) is produced if large amounts of water are lost  Proper concentrations of various electrolytes must be present

25. WATER BALANCE Pituitary senses low blood H 2 O and secretes ADH which makes loop of Henle more permeable to water(water goes out) If blood H 2 O is high, no ADH secreted, Loop of Henle keeps water in If there is more water, urine is clearer

26. Urine 95-99% water The rest is mostly urea (byproduct of protein breakdown by the liver Other waste products are also included in urine. There should be little or no glucose or protein in urine