1. Cell Membrane Gateway to the Cell

2. Cell Membrane The cell membrane is flexible and allows a unicellular organism to move

3. Structure of the Cell Membrane

4. Cell Membrane The cell membrane is made of 2 layers of phospholipids called the phospholipid bilayer

5. Phospholipids Contains 2 fatty acid tails (chains) that are non- polar and one polar head

6. Phospholipids Polar heads are hydrophilic which means “water loving” Non-polar tails are hydrophobic which means “water fearing” Makes membrane selective in what crosses *Hydrophobic molecules pass easily; hydrophilic DO NOT*

8. FLUID- because individual phospholipids and proteins can move around freely within the layer, like it’s a liquid. MOSAIC- because of the pattern produced by the scattered protein molecules when the membrane is viewed from above. FLUID MOSAIC MODEL

9. Types of Transport Across Cell Membranes

10. NORequires NO energy (passive transport) HIGH LOWMolecules move from area of HIGH concentration to area of LOW concentration Diffusion

11. Diffusion of Liquids

12. Diffusion through a Membrane Cell membrane Solute moves DOWN concentration gradient (HIGH to LOW)

13. Osmosis Diffusion of water across a membrane Moves from HIGH water potential (low solute) to LOW water potential (high solute) Diffusion across a membrane Semipermeable membrane

14. Three Forms of Transport Across the Membrane

15. Passive Transport Simple Diffusion Doesn’t require energy Moves from high to low concentration Example: Oxygen or water diffusing into a cell and carbon dioxide diffusing out. Facilitated diffusion Doesn’t require energy Uses transport proteins to move from high to low concentration Examples: Glucose or amino acids moving from blood into a cell.

16. Active Transport Requires energy or ATP Moves materials from LOW to HIGH concentration Moves AGAINST a concentration gradient

17. Isotonic Solution NO NET MOVEMENT OF H 2 O (equal amounts entering & leaving) Hypotonic Solution CYTOLYSIS Hypertonic Solution PLASMOLYSIS

18. Cell in Isotonic Solution CELL 10% NaCL 90% H 2 O 10% NaCL 90% H 2 O ENVIRONMENT NO NET MOVEMENT

19. Cell in Hypotonic Solution ENVIRONMENT CELL 10% NaCL 90% H 2 O 20% NaCL 80% H 2 O ENVIRONMENT

20. Cell in Hypertonic Solution CELL 15% NaCL 85% H 2 O 5% NaCL 95% H 2 O ENVIRONMENT

21. Osmosis in Red Blood Cells IsotonicHypotonicHypertonic

22. Moving the “Big Stuff” Molecules are moved out of the cell by vesicles that fuse with the cell membrane. Exocytosis moving things out This is how many hormones are secreted and how nerve cells communicate with one another.

23. Moving the “Big Stuff” Large molecules move materials into the cell by one of three forms of endocytosis.

24. Pinocytosis Most common form of endocytosis. Takes in dissolved molecules as a vesicle.

25. Receptor-Mediated Endocytosis Some integral proteins have receptors on their surface to recognize & take in hormones, cholesterol, etc.

26. Phagocytosis Used to engulf large particles such as food, bacteria, etc. into vesicles Called “Cell Eating”