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Randomized Comparison of Adjuvant Aromatase Inhibitor Exemestane plus Ovarian Function Suppression vs Tamoxifen plus Ovarian Function Suppression in Premenopausal.

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Presentation on theme: "Randomized Comparison of Adjuvant Aromatase Inhibitor Exemestane plus Ovarian Function Suppression vs Tamoxifen plus Ovarian Function Suppression in Premenopausal."— Presentation transcript:

1 Randomized Comparison of Adjuvant Aromatase Inhibitor Exemestane plus Ovarian Function Suppression vs Tamoxifen plus Ovarian Function Suppression in Premenopausal Women with Hormone Receptor Positive Early Breast Cancer: Joint Analysis of IBCSG TEXT and SOFT Presented By Olivia Pagani at 2014 ASCO Annual Meeting

2 TEXT and SOFT Presented By Olivia Pagani at 2014 ASCO Annual Meeting

3 TEXT and SOFT Worldwide Collaborative Presented By Olivia Pagani at 2014 ASCO Annual Meeting

4 Premenopausal Endocrine Therapy Presented By Olivia Pagani at 2014 ASCO Annual Meeting

5 TEXT - SOFT Trials Aromatase Inhibitor Question Presented By Olivia Pagani at 2014 ASCO Annual Meeting

6 TEXT and SOFT Designs Presented By Olivia Pagani at 2014 ASCO Annual Meeting

7 Eligibility Presented By Olivia Pagani at 2014 ASCO Annual Meeting

8 Treatments Presented By Olivia Pagani at 2014 ASCO Annual Meeting

9 Study Procedures Presented By Olivia Pagani at 2014 ASCO Annual Meeting

10 Endpoints Presented By Olivia Pagani at 2014 ASCO Annual Meeting

11 Statistical Considerations Presented By Olivia Pagani at 2014 ASCO Annual Meeting

12 Characteristics Presented By Olivia Pagani at 2014 ASCO Annual Meeting

13 Exemestane+OFS Improved DFS Presented By Olivia Pagani at 2014 ASCO Annual Meeting

14 Sites of First Failure Presented By Olivia Pagani at 2014 ASCO Annual Meeting

15 Exemestane+OFS Reduced Recurrence Presented By Olivia Pagani at 2014 ASCO Annual Meeting

16 Women Who Did Not Receive Chemotherapy Presented By Olivia Pagani at 2014 ASCO Annual Meeting

17 Women Who Received Chemotherapy Presented By Olivia Pagani at 2014 ASCO Annual Meeting

18 Selected Adverse Events Presented By Olivia Pagani at 2014 ASCO Annual Meeting

19 Adverse Events and QOL Presented By Olivia Pagani at 2014 ASCO Annual Meeting

20 Conclusions Presented By Olivia Pagani at 2014 ASCO Annual Meeting

21 More from TEXT and SOFT Presented By Olivia Pagani at 2014 ASCO Annual Meeting

22 Slide 22 Presented By Olivia Pagani at 2014 ASCO Annual Meeting


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