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Emphysematous abomasitis in one month old lambs

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1 Emphysematous abomasitis in one month old lambs
Hein Snyman BVSc DVSc Anatomic Pathology Resident Department of Pathobiology Ontario Veterinary College University of Guelph

2 Signalment One month old lambs (n=3) Male Rideau Arcott

3 History Novice small scale operation Farmer away on the weekend
Returned to find 3 lambs dead Acute death within last 36 hours Growing well

4 Gross findings Good body condition
Fibrinous peritonitis & serosal petechiae Abomasal mucosal haemorrhage, necrosis and ulceration Exuberant autolysis of the kidney and liver

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15 Gram + Rods

16 Ancillary diagnostics
Faecal flotation – NAD Bacterial culture: 4 + Clostridium perfringens 3 + Mannheimia haemolytica Clostridial Fluorescent antibody test (FAT) Clostridium septicum

17 Diagnosis Mdx - Emphysematous, necrotizing and suppurative abomasitis, trans mural, regionally extensive, acute. Edx - Clostridial gangrenous abomasitis/Braxy Etiology – Clostridium septicum & C. perfringens

18 Braxy Highly fatal Acute to peracute Treatment rarely successful
NW Europe Norway, Denmark, North Germany, Iceland and the Faroe islands – Bradsot UK, Ireland, North America and Australia

19 Braxy Low prevalence Cold winters Overwintering on summer pasture
Autumn, early to mid winter North America – early spring

20 Braxy Severe oedema, necrosis and gangrenous inflammation of the mucosa of the abomasum C. septicum, C. novyi, C. perfringens type A & C

21 Braxy Good condition 6 to 18 months Morbidity up to 50 % Calves
Abomasal ulcers

22 Pathogenesis Poorly understood
Mucosal invasion and proliferation without any predisposing lesion Coarse and frozen vegetation Toxin production Abomasal canula – Glucose & VFA’s Centrifugal emphysematous lesions Ellis T.M., Rowe J.B. and Lloyd J.M. (1983). Acute abomasitis due to Clostridium septicum infection in experimental sheep. Aust. Vet. J. 60,

23 Prevention Immunoprophylaxis Toxoid/Bacterin No vaccination protocol
No Clostridial vaccines

24 References Coetzer J.A.W., Tustin R.C. Infectious diseases of livestock, 2nd Edition, Volume Three, Section Five: Bacterial diseases, 183 Clostidium septicum infections, pg Ellis T.M., Rowe J.B. and Lloyd J.M. (1983). Acute abomasitis due to Clostridium septicum infection in experimental sheep. Aust. Vet. J. 60, Eustis S.L. and Bergeland M.E. (1981). Suppurative abomasitis associated with Clostridium septicum infection. J. Am. Vet. Med. Assoc. 178, Songer JG. (1996). Clostridial enteric diseases of domestic animals. Clin. Microbiol. Rev. 9,


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