1. Research Overview and Core Facilities Larry Cornett, Ph.D. Executive Associate Dean for Research / Vice Chancellor for Research August 22, 2012

2. Chancellor COM Dean Vice Chancellor Research Vice Chancellor Compliance Associate Dean Research Associate Dean Translational Research Special Programs Research Support Center ORSP IRB Research Integrity Bioventures Research Compliance Research COI HIPAA Organizational Structure— UAMS Research

3. UAMS Committees That Govern Research University Research Committee --2 members from each college --manages Student Research Day --Medical Research Endowment Awards --meets monthly Committee for Clinical Research --broad representation across campus (faculty and staff --oversight of support services for clinical/translational research --Chair is Brooks Gentry, M.D.

4. Office of the Vice Chancellor for Research Office of Research and Sponsored Programs— Suzanne Alstadt, Director Institutional Review Board— Jennifer Sharp, J.D., Director UAMS BioVentures— Michael Douglas, Ph.D., Director Research Support Center— Tom Wells, MD, MBA, Director Caroline Miller-Robinson—Business Manager

5. College of Medicine (COM) Research Office Supports COM clinical and basic science research Provides leadership in expanding the College’s research and creative activities Aligns College’s research agenda with federal agencies and foundations Fosters interdisciplinary research programs and collaborations Works with Development Office to further COM research College of Medicine units include: RESNET Services, Division of Laboratory Animal Medicine, Research Council, and MD/PhD Program

6. COM Research Office Personnel Larry Cornett, Ph.D. – Executive Associate Dean for Research, College of Medicine and UAMS Vice Chancellor for Research cornettlawrencee@uams.edu; 501-686-5347 cornettlawrencee@uams.edu Professor, Department of Physiology and Biophysics Director/Principal Investigator - Arkansas INBRE (5/1/10-4/31/15) supported by NIH grant P20 RR016460 Co-Director, UAMS Center for Clinical and Translational Research

7. COM Research Office Personnel Aubrey Hough, M.D. - Associate Dean for Translational Research and Special Programs, College of Medicine houghaubreyj@uams.edu; 501-686-5369 houghaubreyj@uams.edu Professor, Department of Pathology Organized multi-disciplinary group to submit P42 application ($14.8 million, 5 years) to NIEHS and Research Translation Core Worked with interdisciplinary, off-campus consortium on letter of interest to DHS, HHS, and USDA Redrafted UAMS Emergency Preparedness plans including 96 hour JCAHO operations plan

8. COM Research Office Personnel Linda Williams, M.S. - Research Liaison College of Medicine/Vice Chancellor for Research ldwilliams@uams.edu; 501-686-7418 ldwilliams@uams.edu Works with clinical and basic science faculty on research requirements, collaborations, translational interests, funding (FCC, CTSA, ADVANCE) and Development office opportunities, and UAMS/COM research website Maintains statewide Research Communities funding/collaboration website (with funding, conference/seminar information, research facilities, and centers and institute updates); https://secureresearchlink.uams.edu/RCHome.aspx) https://secureresearchlink.uams.edu/RCHome.aspx

9. COM Research Office Personnel Sharon Glover - Program Manager for Special Programs gloversharonr@uams.edu; 501-526-6126 gloversharonr@uams.edu Assists Dr. Hough in proposal preparation, COM Dean’s Distinguished Lecture series, UAMS Emergency Management Committee management, and manages Translational Research and Special Programs budget Linda Laney-Rogers – Project Program Specialist laney-rogerslindac@uams.edu; 501-686-5347 laney-rogerslindac@uams.edu Administrative support for the IACUC and IACUC Chair (Dr. Bill Gurley), COM Research Council and Chair (Dr. Robert McGehee)

10. Research Council Research advisory body for the COM—20 members Reviews and provides support for pilot study and bridging grant proposals Reviews Core Laboratory assessments annually Supports medical student research—Honors Program and Student Research Week Reviews proposed UAMS policies that may potentially impact research

11. Core Facilities http://www.uams.edu/com/research/research_facilities.asp Skeletal Histology and Phenotyping Facility Bioluminescent and Fluorescent Imaging Facility (Xenogen IVIS Imaging System) Flow Cytometry Facility DNA Sequencing Facility Proteomics Facility Digital and Confocal Microscopy Laboratory Experimental Pathology Radiological Imaging Facility (MicroPET) Transgenic Mouse Facility Pharmacogenomics Analysis Laboratory

12. Division of Laboratory and Animal Medicine (DLAM) and the Institutional Animal Care and Use Committee (IACUC) DLAM DLAM under the direction of Mildred Randolph, DVM Provides animal research management, husbandry and care for various animal species (~6100 animals)--mice constitute 81% of the animals Animal facilities locate in the Barton Building, Biomed 1 and 2, and the Cancer Institute include various size animal holding rooms, cubicle rooms, procedure rooms and quarantine room IACUC Animal use protocols submitted to Linda Laney-Rogers – by the 1 st Friday of each month IACUC (Bill Gurley, Ph.D., Chairman) meets –3 rd Friday of each month to review protocols

13. COM Research Website COM Research Home Page - http://www.uams.edu/com/research/default.asp http://www.uams.edu/com/research/default.asp Links: Research News Seminar and Events Calendar COM Core Facilities Funding Opportunities Centers and Institutes Research Council Research Toolbox

14. Research Information Support Network (ReSIN) http://www.uams.edu/research/RESIN_Agenda.asp --Walton Auditorium (Rockefeller Cancer Institute) 1 st Tuesday of each month 12:00-1:00 pm --Open forum that provides important information about research support, new regulations, etc.

15. Questions? http://www.uams.edu/com/research/default.asp