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Nitric Oxide and Prostaglandin E2 Production in Response to Ultra-High Molecular Weight Polyethylene Particles Depends on Osteoblast Maturation State by.

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Presentation on theme: "Nitric Oxide and Prostaglandin E2 Production in Response to Ultra-High Molecular Weight Polyethylene Particles Depends on Osteoblast Maturation State by."— Presentation transcript:

1 Nitric Oxide and Prostaglandin E2 Production in Response to Ultra-High Molecular Weight Polyethylene Particles Depends on Osteoblast Maturation State by Christoph H. Lohmann, David D. Dean, Lynda F. Bonewald, Zvi Schwartz, and Barbara D. Boyan J Bone Joint Surg Am Volume 84(3):411-419 March 1, 2002 ©2002 by The Journal of Bone and Joint Surgery, Inc.

2 Effect of ultra-high molecular weight polyethylene particles on the number of MG63 osteoblast- like cells (A), OCT-1 osteoblast-like cells (B), and MLO-Y4 osteocyte-like cells (C). Christoph H. Lohmann et al. J Bone Joint Surg Am 2002;84:411-419 ©2002 by The Journal of Bone and Joint Surgery, Inc.

3 Effect of ultra-high molecular weight polyethylene particles on the production of prostaglandin E2 by MG63 osteoblast-like cells (A), OCT-1 osteoblast-like cells (B), and MLO-Y4 osteocyte-like cells (C). Christoph H. Lohmann et al. J Bone Joint Surg Am 2002;84:411-419 ©2002 by The Journal of Bone and Joint Surgery, Inc.

4 Effect of ultra-high molecular weight polyethylene particles on the production of nitric oxide (NO) by MG63 osteoblast-like cells (A), OCT-1 osteoblast-like cells (B), and MLO-Y4 osteocyte- like cells (C). Christoph H. Lohmann et al. J Bone Joint Surg Am 2002;84:411-419 ©2002 by The Journal of Bone and Joint Surgery, Inc.


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