Presentation on theme: "DNA: The Genetic Material"— Presentation transcript:
1 DNA: The Genetic Material Chapter 9DNA: TheGenetic Material
2 Just a thought… Make a stack of books totaling about 10,000 pages. That the stack of books representsonly about one-fiftieth of the informationcontained in the DNA ofevery human cell. Correlate thiswith the amount of informationrequired to code for a human being.
5 Answers1. A chromosome consists of two replicated strands of DNA tightly coiled around proteins.The two strands, called chromatids, are attached at a point called a centromere.2. A gene is a segment of DNA that codes for a protein or RNA molecule.3. A cell’s DNA is copied during the synthesis (S) phase.4. When chromosomes break, the broken pieces can detach completely or can reattach in various ways. Therefore, the chromosome is changed, or mutated.
6 5. (a) For each inherited trait, an individual has two copies of the gene, one from each parent. (b) There may be alternative versions of genes.(c) When two different alleles occur together, one of them may be completely expressed, while the other may have no observable effect on the organism’s appearance.(d) When gametes are formed, the alleles for each gene in an individual separate independently of one another, and when gametes unite during fertilization, each gamete contributes one allele.
11 TransformationSomething in the heat-killed bacteria that once were able to produce a capsule that caused them to kill the mice was able to “transform” the once non-virulent bacteria into capsule producing, virulent ones!But what was that something????
12 Avery’s experimentDNA destroying enzymes helped prove it was the DNA not proteins that were the transforming factors!
13 Hershey and Chase used the bacteriophage T2 and radioactive labels to show that viral genes are made of DNA, not protein.
15 The radioactive sulfur remained outside with the protein coat of the virus. The radioactive Phosphorus went inside the bacteria and showed that the DNA was the component that went inside and produced more viral proteins.
16 DNA stores the information that tells cells which proteins to make and when to make them.
17 1. In 1928, the experiments of Griffith demonstrated transformation of a. R bacteria into S bacteria.b. S bacteria into R bacteria.c. heat-killed S bacteria into R bacteria.d. S bacteria into heat-killed R bacteria.2. In 1952, Hershey and Chase used the bacteriophage T2 to determine that genetic material is made of which of the following?a. protein c. DNAb. RNA d. 35S3. A microorganism that is virulent isa. able to cause disease. c. a bacteriophage.b. transformed. d. harmless.
18 4. Avery’s experiments showed that a. DNA is responsible for transformation.b. proteins are responsible for transformation.c. bacteriophages are responsible for transformation.d. virulent bacteria are responsible for transformation.5. Hershey and Chase injected phages witha. S bacteria. c. radioactive isotopes.b. R bacteria. d. vaccines.6. Hershey and Chase found that T2 bacteriophagesa. inject their DNA into host cells.b. cause host cells to produce viral DNA and proteins.c. keep most of their viral proteins outside the host cell.d. All of the above
19 ______ 7. radioactive sulfur and phosphorous ______ 8. transformation______ 9. bacteriophage______10. vaccinea. discovered by Griffithb. infects bacteriac. used in the Hershey and Chase experimentsd. helps protect the body against future infections by specific disease-causing agents
20 GENETIC MATERIAL answers 1. a 6. d2. c 7. c3. a 8. a4. a 9. b5. c d
21 2. The Structure of DNA A. A Winding Staircase B. Discovering DNA’s Structure
22 The Structure of DNADNA is made of two strands of nucleotides twisted into the form of a double helix.
23 Each nucleotide in DNA is made of the sugar deoxyribose, a phosphate group, andone of four nitrogen bases.The four nitrogen bases found in DNA nucleotides areadenine (A),thymine (T),guanine (G),andcytosine (C).
24 The two strands of DNA are complementary—each A on one strand pairs with a T on the opposite strand, and each G on one strand pairs with a C on the opposite strand.
25 Watson and Crick announced their discovery of the structure of DNA in 1953 with the help of data gathered by Wilkins, Franklin, and Chargaff.
27 3. The Replication of DNA A. The Roles of Enzymes in DNA Replication Summarize the steps of DNA replication
28 B. The Rate of Replication p 200 To go fast, there are multiple replication forks!
29 The Replication of DNABefore a cell divides, it copies its DNA by a process called DNA replication.In DNA replication, enzymes work to unwind and separate the double helix and add complementary nucleotides to the exposed strands.
30 The result of DNA replication is two exact copies of the cell’s original DNA. Each new double helix is composed of one original DNA strand and one new DNA strand..
31 DNA polymerase proofreads DNA during its replication so that very few errors occur