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Turnover of fibrillar collagen in soft biological tissue with application to the expansion of abdominal aortic aneurysms by Giampaolo Martufi, and T. Christian.

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Presentation on theme: "Turnover of fibrillar collagen in soft biological tissue with application to the expansion of abdominal aortic aneurysms by Giampaolo Martufi, and T. Christian."— Presentation transcript:

1 Turnover of fibrillar collagen in soft biological tissue with application to the expansion of abdominal aortic aneurysms by Giampaolo Martufi, and T. Christian Gasser Interface Volume 9(77):3366-3377 December 7, 2012 ©2012 by The Royal Society

2 The hierarchical structure of a collagen fibre built-up of statistically distributed collagen fibrils that are interlinked by proteoglycan (PG) bridges and populated by fibroblast cells. Giampaolo Martufi, and T. Christian Gasser J. R. Soc. Interface 2012;9:3366-3377 ©2012 by The Royal Society

3 Finite strain kinematics of the collagenous tissue. Giampaolo Martufi, and T. Christian Gasser J. R. Soc. Interface 2012;9:3366-3377 ©2012 by The Royal Society

4 Evolution of the abdominal aortic aneurysm (AAA) tube model over time with respect to different undulations of the newly formed collagen fibrils. Giampaolo Martufi, and T. Christian Gasser J. R. Soc. Interface 2012;9:3366-3377 ©2012 by The Royal Society

5 Calibration of the abdominal aortic aneurysm (AAA) tube model (thick line) with respect to clinical follow-up data (thin lines) of small AAAs. Giampaolo Martufi, and T. Christian Gasser J. R. Soc. Interface 2012;9:3366-3377 ©2012 by The Royal Society

6 Maximum principal Cauchy stress computed with the abdominal aortic aneurysm (AAA) tube model. Giampaolo Martufi, and T. Christian Gasser J. R. Soc. Interface 2012;9:3366-3377 ©2012 by The Royal Society

7 Stress and shape development of a patient-specific abdominal aortic aneurysm (AAA) model. Giampaolo Martufi, and T. Christian Gasser J. R. Soc. Interface 2012;9:3366-3377 ©2012 by The Royal Society

8 Numerically predicted collagen distribution in the abdominal aortic aneurysm (AAA) wall. Giampaolo Martufi, and T. Christian Gasser J. R. Soc. Interface 2012;9:3366-3377 ©2012 by The Royal Society

9 Development of the maximum principal Cauchy stress in the abdominal aortic aneurysm (AAA) wall after 2, 5 and 10 years. Giampaolo Martufi, and T. Christian Gasser J. R. Soc. Interface 2012;9:3366-3377 ©2012 by The Royal Society


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