Presentation is loading. Please wait.

Presentation is loading. Please wait.

4 th Yearly Meeting of the Coordinators of the Centres of Excellence LIFE/MED Eva Syková

Similar presentations

Presentation on theme: "4 th Yearly Meeting of the Coordinators of the Centres of Excellence LIFE/MED Eva Syková"— Presentation transcript:

1 4 th Yearly Meeting of the Coordinators of the Centres of Excellence LIFE/MED Eva Syková

2 ARICY Agricultural Research Institute, Nicosia, Cyprus BIER Jagiellonian University, Faculty of Biotechnology, Krakow, Poland BIOREGION-SZEGED Biological Research Centre, HAS, Szeged, Hungary BLOODVESSELS Institute of Cellular Biology and Pathology, Romania CEBIOLA Vilnius University, Vilnius, Lithuania CENEXFOOD Inst. of Animal Reproduction and Food Research, PAS, Olsztyn, Poland DESMOL Centre of Molecular and Macromolecular Studies, PAS, Lodz, Poland EMBEU Institute of Biochemistry and Biophysics, PAS, Warsaw, Poland EURO-NEURO-NETWORKSInstitute of Experimental Medicine, HAS, Budapest, Hungary EXCELLENT PLANT BIOTECH AgroBioInstitute, Sofia, Bulgaria GENEMILL Estonian Biocentre, Tartu, Estonia MEDIPRA Institute of Experimental Medicine, ASCR, Prague, Czech Republic STRESSNUTS Institute of Experimental Endocrinology, SAS, Bratislava, Slovakia EU Centres of Excellence Bio-Med parallel Group

3 CoE Acronym: EXCELLENT PLANT BIOTECH AgroBioInstitute, (ABI), Sofia, Bulgaria Coordinators: Prof. Atanas Atanassov Dr. Ivan Atanassov Promoting of sustainable and environment friendly agriculture through development, adoption and application of up to date biotechnology methods and know-how

4 CoE Excellent Plant Biotech: years of expending research and networking capacity 2000Institute of Genetic Engineering (starting of CoE project) 2001AgroBioInstitute (extanding of agrobiotech applications) 2002new location of AgroBioInstitute (modern research facilities) 2003AgroBioTech Park (joining of reserach, training and business activities) 2004Biotechnology Information Center and Genome Center (public relations, genomics and metabolomics)

5 Agricultural Research Institute, ARICY Coordinator I. Papadopoulos Engaged in applied and basic research in plant and animal production Provide high quality scientific results, environmentally and socially sustainable

6 The genetic basis of Scrapie and the utilization of molecular techniques for its control in sheep 1 2 3 4 5 6 7 Polymorphic codon genotypes are: 171 Arg/Arg (lanes 1, 2, 3, 5, 6) and 171 Arg/Gln (lanes 4, 7) The infection is associated with the PrP gene. The allelomorph RR is associated with resistance to the disease. The onjective is to increase the frequency of resistant genotypes in the population.

7 Mission: Basic research in neuroscience, genetic ecotoxicology, cell biology and molecular pharmacology. Bridging the gap between basic research and clinical application. Institute of Experimental Medicine Academy of Sciences of the Czech Republic MEDIPRA Coordinator: Professor Eva Syková

8 European collaborations in MEDIPRA

9 Mechanisms underlying development, aging, neurodegenerative diseases, brain and spinal cord injury Stem cell research, in vivo MR tracking of implanted stem cells using superparamagnetic nanoparticles Propagation and controlled differentiation of human embryonic stem cells Molecular epidemiological studies: Biomarkers of exposure to mutagens and carcinogens and the embryotoxicity of genotoxic compounds Most important scientific results

10 Clinical study Bone marrow stem cell implantation to treat spinal cord injury Most important scientific results

11 Estonian Biocentre, GENEMILL Main Mission: Basic and applied research in molecular medicine and human genomics


13 Bioregion-Szeged Biological Research Center Hungarian Academy of Sciences Szeged, Hungary CoE: BIOREGION-Szeged Regional Initiative for Improvement of Quality of Life through Research, Education, and Innovation in Molecular and Cell Biology Biological Research Center, Hungarian Academy of Sciences Coordinator: Prof. DÉNES DUDITS

14 Training: schools, symposia Bioinformatics: PL, HU ITC lecture course and practicals (yearly) Biophysics: –Molecular structures and dynamics of energy converting membranes (23. June-2. July 2001) 32 invited speakers from 11 European countries, the school was attended by 42 students from 11 European countries Biological Research Center Hungarian Academy of Sciences Szeged, Hungary CoE: BIOREGION-Szeged

15 Research deliverables 15 work packages More than 150 refereed publications Outstanding activities –Plant cell and molecular biology –Nanobiotechnology Light-driven micromachinery produced and driven by light produced and driven by light Molecular structure of the NORK protein Nitrogen fixing root nodules Biological Research Center Hungarian Academy of Sciences Szeged, Hungary CoE: BIOREGION-Szeged

16 Cell Biology and Lasers: Towards New Technologies CEBIOLA Coordinators:Prof. Benediktas Juodka Prof. Algis Piskarskas The mission of the center: to promote research, advanced studies and training in the field where cell biology meets light technologies giving birth to diverse and ever-widening range of laser applications in life sciences Vilnius University, Lithuania

17 ALA-injection Laser treatment Accumulation Necrosis PHOTOSENSITIZED LASER TUMOUR THERAPY 700 patients treated successfully in Lithuania

18 LASERNET/LASERLAB-EUROPE LENS: Firenze, Italy ULF-FORTH: Iraklion, Greece LIF-LOA: Palaiseau, France LLC: Lund, Sweden LCVU: Amsterdam, Netherlands MBI: Berlin, Germany LULI: Palaiseau, France CLF: Chilton, England GSI: Darmstadt, Germany PALS: Prague, Czech Republic CEA: Saclay, France TU Vienna: Vienna, Austria CEA: Bordeaux, France LRC VU: Vilnius, Lithuania CELIA: Bordeaux, France CUSBO: Milano, Italy

19 Molecular Biotechnology - Integration of Education and Research BIER Jagiellonian University, Faculty of Biotechnology Krakow, Poland Main mission of the Centre BIER: Combining research and teaching of molecular biotechnology at the European level Co-ordinator: Professor Aleksander Koj

20 Substantial progress in understanding of molecular mechanisms of stress tolerance in plant cells: -- Elucidation of the effect of heavy metals on formation of photosynthetic apparatus; -- Description of the cyclic electron flow around photosystem II in overexcitation conditions with a special emphasis on cytochrome b 559. The most important scientific result (one selected from many): The model showing photoreduction sites of cyt c in thylakoids under low and medium light intensity (black cyt c symbol) and occurring additionally at high light intensities (white cyt c symbol). The action sites of the used electron transport inhibitors are also shown.

21 The most important outcome of BIER activity: International recognition of BIER as an expert teaching and research centre in molecular biotechnology Promotion of the Institute of Molecular Biology to the Faculty of Biotechnology located on a new Campus and offering full curriculum in biotechnology

22 Main mission: training of young researchers in FOOD SCIENCE training of young researchers in FOOD SCIENCE promoting trans-border mobility promoting trans-border mobility pan-European networking pan-European networking Co-ordinator: Prof. Halina Kozłowska CENTRE OF EXCELLENCE FOR KNOWLEDGE TRANSFER, RESEARCH AND EDUCATION IN FOOD AND HEALTH for CENTRAL & EASTERN EUROPE CENEXFOOD

23 Exceptionally good relationship between scientists form Olsztyn and Norwich led to start the process of twining of both cities (Sister Cities). From science to local scocieties

24 DESMOL – Designed Molecules and Macromolecules Their Assemblies and Biological Functions Center of Molecular and Macromolecular Studies, Łódź, Poland Coordinators: Professor Marian Mikołajczyk Professor Przemysław Kubisa about 130 researchers and PhD students involved Mission: - to combine the research activity and expertise of research teams working in the area of heteroorganic chemistry, bioorganic chemistry and macromolecular science - to develop new interdisciplinary approaches to molecular and macromolecular engineering, aimed at manufacturing of new materials for applications in medicine and modern technology.

25 DESMOL – Designed Molecules and Macromolecules Their Assemblies and Biological Functions Center of Molecular and Macromolecular Studies, Łódź, Poland Melting temperature increases by 50 0 C (wider range of application) Most important scientific result: New biodegradable materials based on polymers with special topologies (star-polymers and their stereocomplexes) obtained from renewable sources (lactic acid) Those materials may serve as biodegradable comodity plastics or specialty materials for application in medicine.

26 Centre of Excellence in Molecular Biotechnology EMBEU Coordinator: Prof. Andrzej Rabczenko Institute of Biochemistry and Biophysics Polish Academy of Sciences Warsaw, Poland Member of Ochota Campus Consortium

27 EMBEU achievements selected from over 80 publications Proteomics study resulting in identification of new markers for Alzheimers disease Novel inhibitors of HCV helicase Application of comparative genomics for identification of new protein targets to fight malaria New technology to use protease inhibitors in drug protection (patented) Genomics of clinically relevant plasmids

28 EMBEU activity Exchange visits Organization of conferences, numerous workshops and courses Networking other CoEs (Cyprus, Bulgaria, Hungary, Poland) Inducing 4 new CoEs in our campus Promotion of the European cooperation resulting in 15 FP5 and FP6 projects Establishment of FP5 Marie Curie Training Site – Education and Research in Molecular Biology

29 Institute of Cellular Biology and Pathology Nicolae Simionescu ROMANIAN ACADEMY Member of UNESCO Global Network for Molecular and Cell Biology Center of Excellence: Blood Vessels Coordinator: Dr. Maya Simionescu Research Program Understanding the molecular and cellular mechanisms occurring in the normal vessels, and the alterations of the arterial wall leading to the cardiovascular diseases Title of the project Function and dysfunction of blood vessels: transcytosis in normal/pathological states, alterations in atherosclerosis and diabetes; their therapeutic control Our Credo : Cellular and Molecular Biology for the Benefit of Human Health

30 Anti-atherogenic drugs effects tested on the hyperlipemic and/or hyperglycemic hamster: statins (simvastatin, atorvastatin); statins (simvastatin, atorvastatin); calcium channel blockers (nifedipine, amlodipine); calcium channel blockers (nifedipine, amlodipine); ACE inhibitors (enalapril, captopril); ACE inhibitors (enalapril, captopril); anti-thrombotic (enoxaparin, aspirin); anti-thrombotic (enoxaparin, aspirin); vitamins (E and C); vitamins (E and C); L-Arginine; L-Arginine; "intelligent liposomes" for an efficient drug delivery. "intelligent liposomes" for an efficient drug delivery. Pharmacological Modulation of Endothelial Cell Function The effect of drugs on the cells of the vascular wall The effect of drugs on the cells of the vascular wall EC depend relaxation EC depend relaxation = Structure = Structure Arterial pressure Arterial pressure Atherosclerosis Atherosclerosis

31 STRESSNUTS Institute of Experimental Endocrinology Slovak Academy of Sciences Bratislava, Slovakia Coordinator: Assoc. Prof. Daniela Ježová Main mission of this Centre To provide experimental and clinical data leading to specific recommendations aimed at reducing the negative impact of environmental factors on human health

32 Most important scientific result (one selected from many) Evidence has been obtained to support further clinical research on the following substances to modulate hormone release and treat the negative impact of demanding stressful situations, anxiety and depression: mood stabilizers extract of Ginkgo biloba pentoxifylline antidepressants selected amino acids placebo lamotrigine STRESSNUTS

33 In all EU Centers of excellence the program has greatly contributed towards: Mobility of scientists Exchange of experience and know-how Training at all levels Through networking and twinning, excellent co-operation has been realized Consortiums of scientists and institutions for joint projects for the 6 th FP have been established

34 Increased international recognition of the Institutes Participation of scientists in the 5 th and 6 th FP Success in obtaining national and international funding Expansion of the Institutes Strengthened collaborationin EU Start of clinical studies based on research conducted in the CoE Appointment of several outstanding young researchers Increased quality of scientific results and of publications New training activities, teaching courses Public lectures and press conferences Most important outcomes of the CoE programme:

35 The program has undoubtedly fulfilled its purposes. It has contributed immensely towards the spirit of co-operation and exchange of scientific information between the scientific community This indisputable fact should be further promoted and supported (morally and financially) by engaging in similar programs for the benefit of the peoples of the new members of the United Europe CoE Projects - bridge to the EU

Download ppt "4 th Yearly Meeting of the Coordinators of the Centres of Excellence LIFE/MED Eva Syková"

Similar presentations

Ads by Google