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Session II: Scientific Publishing and Semantic Web W3C Semantic Web for Life Sciences Workshop October 27, 2004 Moderator: Alan R. Aronson.

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Presentation on theme: "Session II: Scientific Publishing and Semantic Web W3C Semantic Web for Life Sciences Workshop October 27, 2004 Moderator: Alan R. Aronson."— Presentation transcript:

1 Session II: Scientific Publishing and Semantic Web W3C Semantic Web for Life Sciences Workshop October 27, 2004 Moderator: Alan R. Aronson

2 Foundations of Semantic Text Processing at NLM Alan R. Aronson (National Library of Medicine) Urchin RSS / The Urchin/Kowari Project Ben Lund, David Wood (Nature Publishing Group, Tucana Technologies) Semantic Web and Elsevier Marc Krellenstein (Elsevier) Semantic Web for Data Interpretation & Integration: Lessons Learned from Scientific Publishing and the Distributed Annotation System Steve Chervitz (Affymetrix)

3 Foundations of Semantic Text Processing at NLM Alan R. Aronson, PhD National Library of Medicine W3C Semantic Web for Life Sciences Workshop October 27, 2004

4 Outline Unified Medical Language System (UMLS) Knowledge Sources The MetaMap Program The NLM Indexing Initiative SemRep (Semantic Representation)

5 The Unified Medical Language System UMLS Knowledge Sources Metathesaurus Semantic Network SPECIALIST Lexicon MetamorphoSys (Metathesaurus subset extraction) Lexical/spelling tools (lvg, norm, Gspell) Knowledge Source Server

6 MetaMap Maps text to the Metathesaurus Parse text into phrases Generate word variants Retrieve Metathesaurus candidates Evaluate candidates against text phrases Form final mapping Linguistically rigorous Partial matching Web interface and Java-based application

7 NLM Indexing Initiative (II) Investigate automated and semi-automated indexing methodologies Develop methods that result in acceptable retrieval performance Concept-based algorithms Extensive use of UMLS resources Medical Text Indexer (MTI), a tool for semi-automated assistance in MEDLINE indexing automatic indexing of some abstracts collections

8 SemRep Family of programs to extract semantic relationships from biomedical text SemRep (the progenitor) Arbiter (binding relationships) EDGAR (drug-gene relationships) SemSpec (hypernymic propositions) SemGen (etiology of genetic diseases)

9 Language and Meaning Language Meaning Semantic Interpretation Semantic Relation(Concept,Concept) World Model Relations Entities Words Syntactic Structure Predicates Arguments

10 Lexical Look-up and Tagger combinationchemotherapy noun aggressive adj in prep the det management noun failure of prep hypercalcemic adj renal noun

11 Parser combination noun mod chemotherapy noun head aggressive adj mod in prep the det management noun head failure of prep hypercalcemic adj mod renal noun mod noun head NP

12 MetaMap in prep the det management noun head NP failure of prep hypercalcemic adj mod renal noun mod noun head NP combination noun mod chemotherapy noun head aggressive adj mod NP Drug Therapy, Combination topp Disease or Syndrome Kidney Failure dsyn Therapeutic or Preventive Procedure

13 SemRep in prep the det management noun head NP failure of prep hypercalcemic adj mod renal noun mod noun head NP combination noun mod chemotherapy noun head aggressive adj mod NP Drug Therapy, Combination topp Kidney Failure dsyn Dependency grammar applies syntactic constraints for nominalization

14 SemRep in prep the det management noun head NP failure of prep hypercalcemic adj mod renal noun mod noun head NP combination noun mod chemotherapy noun head aggressive adj mod NP Drug Therapy, Combination topp Kidney Failure dsyn TREATS Match semantic types between arguments and Semantic Network medd-TREATS-dsyn phsu-TREATS-dsyn topp-TREATS-dsyn topp-TREATS-inpo topp-TREATS-sosy topp-TREATS-anab

15 NLM Web Pointers UMLS Knowledge Source Server: http://umlsks.nlm.nih.gov/ http://umlsks.nlm.nih.gov/ Semantic Knowledge Representation Project: http://skr.nlm.nih.gov/ http://skr.nlm.nih.gov/ NLM Indexing Initiative: http://ii.nlm.nih.gov/http://ii.nlm.nih.gov/


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