Lab Subcommittee: Completed Steps Model Prototypes Viral Resistance Genotyping Human Tissue Transplant Rejection Markers Human Drug Metabolism Markers Fit Standard Use Cases to Model Revise model Add Known Variant Use Cases E.g. Reinterpretation of a Viral Sequence
Lab Subcommittee: In Progress Isolate and Standardize Common Elements Sequence, Codon, SNP, etc. Refine model with Standard Elements Fit Real Data to Model
Future Lab Model Extensions Additional Pharmacogenomics Processes Microarray Data Scientific Extensions Addition of nonSNP Genomic data (e.g. Introns) Interpretation of multiple HIV Strains
Next Steps Define Relation to New HL7-I3C- CDISC-FDA Effort Flow from Preclinical to Lab to Operational to Analysis and Submissions Models Common Large Models with Subsetted Implementations Refinement of Common Data Structures Sequence, Codon, SNP, etc.