1. Notes: The History of the Microscope

2. Magnifying Glass, 13 th C First used as a “burning glass” Began being used to improve vision in the early 13 th century

3. Glass Lens, 1268 Discovered by Roger Bacon in 1268 Began use in eyeglasses between 1268 and 1289

4. Telescope, 16 th C Invented by Hans Lippershay Improved by Galileo Galilei, who was the pioneer for modern astronomy

5. First Microscope, late 16 th C Basically, this was a tube with a plate at one end and a lens at the other Magnified objects 10X

6. Improvements Zaccharias Jansseen, and his son Hans, added a second lens in 1597

7. Marcello Malphighi Studied human “physiology” (cells of the human body) Worked from 1653 until his death in 1694

8. Robert Hooke First looked at cork under the microscope; gave them the name “cells” Wrote the book Micrographia in 1665 Considered the “English father of microscopy” Developed and used the compound microscope

9. Antoni van Leeuwenhoek Dutch maker of microscopes Also called the “father of microscopy” Was able to invent a microscope that magnified 270X Made over 500 microscopes

10. Microscopes of Today Compound microscope: creation of microscope stages and clips, slides, and objective lenses; smooth focus and magnification; uses 2 lenses

11. Electron Microscope Uses electrons to light up an image Electron gun emits electrons in a vacuum Electrons strike substance and image is recorded on a computer monitor Two Types-

12. Two Types of Electron Microscopes 1.Transmission Electron Microscope (TEM)- looks at large samples 2.Scanning electron microscope (SEM)- looks at thinly cut samples

13. Scanning Probe Microscope Uses a probe to scan the surface of a sample and provides a 3-D image Probe has a sharp metal point (single atom thick at the tip) Probe moves up and down over the surface of the object and feeds data into a computer, which provides the image